ArticleBiological cybernetics2021
Making decisions in the dark basement of the brain: A look back at the GPR model of action selection and the basal ganglia.
Article in Biological cybernetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 2 citations in OpenAlex.
- 10-year longitudinal dopamine D2-receptor losses are associated with cognitive decline in healthy aging.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Quantifying harmony between direct and indirect pathways in the basal ganglia: healthy and Parkinsonian states.Cognitive neurodynamics · 2024Article
- Break-up and recovery of harmony between direct and indirect pathways in the basal ganglia: Huntington's disease and treatment.Cognitive neurodynamics · 2024Article
- Simulated Dopamine Modulation of a Neurorobotic Model of the Basal Ganglia.Biomimetics (Basel, Switzerland) · 2024Article
- Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease.Current opinion in neurobiology · 2023Review
- Rethinking the network determinants of motor disability in Parkinson's disease.Frontiers in synaptic neuroscience · 2023Review
- Mathematization of nature: how it is done.Biological cybernetics · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How does your brain decide what you will do next? Over the past few decades compelling evidence has emerged that the basal ganglia, a collection of nuclei in the fore- and mid-brain of all vertebrates, are vital to action selection. Gurney, Prescott, and Redgrave published an influential computational account of this idea in Biological Cybernetics in 2001. Here we take a look back at this pair of papers, outlining the "GPR" model contained therein, the context of that model's development, and the influence it has had over the past twenty years. Tracing its lineage into models and theories still emerging now, we are encouraged that the GPR model is that rare thing, a computational model of a brain circuit whose advances were directly built on by others.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.