Evidence map›Paper›PMID 34272649›Full record

ArticleJournal of autism and developmental disorders2022

Sex Differences in Functional Connectivity Between Resting State Brain Networks in Autism Spectrum Disorder.

Vânia Tavares, Luís Afonso Fernandes, Marília Antunes, Hugo Ferreira, Diana Prata

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vânia TavaresFaculdade de Ciências, Instituto de Biofísica e Engenharia Biomédica, Universidade de Lisboa, Campo Grande, 1749-016, Lisboa, Portugal. vstavares@fc.ul.pt.
Luís Afonso FernandesServiço de Psiquiatria, Hospital Prof. Doutor Fernando Fonseca, EPE, IC 19, 2720-276, Amadora, Portugal.
Marília AntunesFaculdade de Ciências, Centro de Estatística e Aplicações, DEIO, Universidade de Lisboa, Campo Grande 016, 1749-016, Lisboa, Portugal.
Hugo Ferreira *Faculdade de Ciências, Instituto de Biofísica e Engenharia Biomédica, Universidade de Lisboa, Campo Grande, 1749-016, Lisboa, Portugal.
Diana Prata *Faculdade de Ciências, Instituto de Biofísica e Engenharia Biomédica, Universidade de Lisboa, Campo Grande, 1749-016, Lisboa, Portugal. diana.prata@kcl.ac.uk.ORCID http://orcid.org/0000-0002-4051-022X

Funding

Fundação Bial 2017Fundação para a Ciência e a Tecnologia DSAIPA/DS/0065/2018Fundação para a Ciência e a Tecnologia IF/00787/2014Fundação para a Ciência e a Tecnologia UID/MAT/00006/2013Fundação para a Ciência e Tecnologia PD/BD/114460/2016H2020 Marie Skłodowska-Curie Actions FP7-PEOPLE-2013-CIG 631952iMM Lisboa 2016 Breakthrough Idea Grant
6 · The paper itself

Abstract

Functional brain connectivity (FBC) has previously been examined in autism spectrum disorder (ASD) between-resting-state networks (RSNs) using a highly sensitive and reproducible hypothesis-free approach. However, results have been inconsistent and sex differences have only recently been taken into consideration using this approach. We estimated main effects of diagnosis and sex and a diagnosis by sex interaction on between-RSNs FBC in 83 ASD (40 females/43 males) and 85 typically developing controls (TC; 43 females/42 males). We found increased connectivity between the default mode (DM) and (a) the executive control networks in ASD (vs. TC); (b) the cerebellum networks in males (vs. females); and (c) female-specific altered connectivity involving visual, language and basal ganglia (BG) networks in ASD-in suggestive compatibility with ASD cognitive and neuroscientific theories.

Indexed as

Autism Spectrum DisorderBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysSex CharacteristicsAutism spectrum disorderFunctional connectivityFunctional magnetic resonance imagingIndependent component analysisResting-state networks

Identifiers

PMID34272649
PMCPMC9213274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.