Evidence map›Paper›PMID 34272559›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022

Deliberation, Dissent, and Distrust: Understanding Distinct Drivers of Coronavirus Disease 2019 Vaccine Hesitancy in the United States.

Khai Hoan Tram, Sahar Saeed, Cory Bradley, Branson Fox, Ingrid Eshun-Wilson, Aaloke Mody, Elvin Geng

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  12. The 2Human vaccines & immunotherapeutics · 2024
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  13. Correlates of COVID-19 vaccination status among college students.Journal of American college health : J of ACH · 2024
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khai Hoan TramDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.ORCID 0000-0003-1129-7674
Sahar SaeedDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.
Cory BradleyDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.
Branson FoxDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.
Ingrid Eshun-WilsonDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.
Aaloke ModyDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.
Elvin GengDivision of Infectious Diseases, Department of Medicine, Washington University in St Louis, St Louis, Missouri, USA.

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
NCATS NIH HHS KL2 TR002346
6 · The paper itself

Abstract

backgroundDespite the availability of safe and efficacious coronavirus disease 2019 vaccines, a significant proportion of the American public remains unvaccinated and does not appear to be immediately interested in receiving the vaccine.

methodsIn this study, we analyzed data from the US Census Bureau's Household Pulse Survey, a biweekly cross-sectional survey of US households. We estimated the prevalence of vaccine hesitancy across states and nationally and assessed the predictors of vaccine hesitancy and vaccine rejection. In addition, we examined the underlying reasons for vaccine hesitancy, grouped into thematic categories.

resultsA total of 459 235 participants were surveyed from 6 January to 29 March 2021. While vaccine uptake increased from 7.7% to 47%, vaccine hesitancy rates remained relatively fixed: overall, 10.2% reported that they would probably not get a vaccine and 8.2% that they would definitely not get a vaccine. Income, education, and state political leaning strongly predicted vaccine hesitancy. However, while both female sex and black race were factors predicting hesitancy, among those who were hesitant, these same characteristics predicted vaccine reluctance rather than rejection. Those who expressed reluctance invoked mostly "deliberative" reasons, while those who rejected the vaccine were also likely to invoke reasons of "dissent" or "distrust."

conclusionsVaccine hesitancy comprises a sizable proportion of the population and is large enough to threaten achieving herd immunity. Distinct subgroups of hesitancy have distinctive sociodemographic associations as well as cognitive and affective predilections. Segmented public health solutions are needed to target interventions and optimize vaccine uptake.

Indexed as

COVID-19VaccinesCOVID-19 VaccinesCross-Sectional StudiesDissent and DisputesFemaleHumansSARS-CoV-2United StatesVaccinationVaccination HesitancyCOVID-19 VaccinesVaccinesCOVID-19COVID-19 vaccinevaccine hesitancy

Identifiers

PMID34272559
PMCPMC8406882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.