ArticleThe ISME journal2022
Cytokinin drives assembly of the phyllosphere microbiome and promotes disease resistance through structural and chemical cues.
Article in The ISME journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- How Useful Are Plant Traits in Explaining Variation in Phyllosphere Microbial Abundance and Composition Across Hosts?Environmental microbiology · 2025Pooled it
- It takes a village: how plant-associated bacterial communities socialise to shape plant growth and health.Essays in biochemistry · 2026Review
- Keystone taxa of phyllosphere microbiome confer resistance to citrus bacterial canker in pomelo via multiple mechanisms.Journal of integrative plant biology · 2026Article
- Synthetic communities and metabolite-driven enrichment of keystone rhizosphere microbial taxa suppress bacterial wilt disease in peanut.Plant communications · 2026Article
- Leaf development is associated with coupled metabolome-fungi trajectories in the phyllosphere of Panax ginseng.BMC plant biology · 2026Article
- Prosystemin-derived signals: bridging leaf microbiome dynamics and defense activation.Environmental microbiome · 2026Article
- The plant microbiota: From theoretical advances to applications.Fundamental research · 2026Review
- Phyllosphere microbiome: Exploring the unexplored frontiers for precision agricultural and environmental sustainability.World journal of microbiology & biotechnology · 2026Review
- Foliar application of microbial consortium formulations suppresses Phomopsis leaf blight, promotes vegetative growth, and modulates biochemical defence in strawberry (Frontiers in plant science · 2026Article
- Microbial SynComs as biocontrol tools: modulating plant immunity and future perspectives.Frontiers in microbiology · 2026Article
- From Leaves to Roots: How Foliar IAA Application Alters Fungal Network in the Rhizosphere and Endosphere of Eucommia ulmoides.Current microbiology · 2025Article
- Leaf Developmental Stage Influences Disease Resistance in Tomato.Molecular plant pathology · 2025Article
- Common garden experiments suggest terpene-mediated associations between phyllosphere microbes and Japanese cedar.Scientific reports · 2025Article
- Phyllosphere synthetic microbial communities: a new frontier in plant protection.BMC plant biology · 2025Review
- Host selection is not a universal driver of phyllosphere community assembly among ecologically similar native New Zealand plant species.Microbiome · 2025Article
- Differential responses of root and leaf-associated microbiota to continuous monocultures.Environmental microbiome · 2025Article
- Divergence and convergence in epiphytic and endophytic phyllosphere bacterial communities of rice landraces.mSphere · 2024Article
- Employing Bacillus and Pseudomonas for phytonematode management in agricultural crops.World journal of microbiology & biotechnology · 2024Review
- Endophytic Microorganisms in Tomato Roots, Changes in the Structure and Function of the Community at Different Growing Stages.Microorganisms · 2024Article
- Isolation of endophytes from Dioscorea nipponica Makino for stimulating diosgenin production and plant growth.Plant cell reports · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant hormone cytokinin (CK) is an important developmental regulator, promoting morphogenesis and delaying differentiation and senescence. From developmental processes, to growth, to stress tolerance, CKs are central in plant life. CKs are also known to mediate plant immunity and disease resistance, and several classes of microbes can also produce CKs, affecting the interaction with their plant hosts. While host species and genotype can be a driving force in shaping the plant microbiome, how plant developmental hormones such as CK can shape the microbiome is largely uninvestigated. Here, we examined the relationship between CK and the phyllosphere microbiome, finding that CK acts as a selective force in microbiome assembly, increasing richness, and promoting the presence of Firmicutes. CK-mediated immunity was found to partially depend on the microbial community, and bacilli isolated from previously described CK-rich plant genotypes, which overexpress a CK biosynthesis gene or have increased CK sensitivity, induced plant immunity, and promoted disease resistance. Using a biomimetic system, we investigated the relationship between the leaf microstructure, which is differentially patterned upon changes in CK content or signaling, and the growth of different phyllosphere microbes. We found that leaf structures derived from CK-rich plant genotypes support bacilli in the biomimetic system. CK was able to promote the growth, swarming, and biofilm formation of immunity inducing bacillus isolates in vitro. Overall, our results indicate that host genotype and hormonal profiles can act as a strong selective force in microbiome assembly, underlying differential immunity profiles, and pathogen resistance as a result.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.