Evidence map›Paper›PMID 34272410›Full record

ArticleScientific reports2021

Immunomodulatory role of Parkinson's disease 7 in inflammatory bowel disease.

Rita Lippai, Apor Veres-Székely, Erna Sziksz, Yoichiro Iwakura, Domonkos Pap, Réka Rokonay, Beáta Szebeni, Gábor Lotz, Nóra J Béres, Áron Cseh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Anti-fibrotic effect ofFrontiers in bioengineering and biotechnology · 2026
    Article
  3. Article
  4. Review
  5. Comparison of MicroalgaeMarine drugs · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. High Salt Promotes Inflammatory and Fibrotic Response in Peritoneal Cells.International journal of molecular sciences · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. PARK7/DJ-1 as a Therapeutic Target in Gut-Brain Axis Diseases.International journal of molecular sciences · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Rita Lippai1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Apor Veres-Székely1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Erna Sziksz1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Yoichiro IwakuraResearch Institute for Biomedical Sciences and Center for Animal Disease Models, Research Institute for Science and Technology, Tokyo University of Science, Tokyo, Japan.
Domonkos PapELKH-SE Pediatrics and Nephrology Research Group, Budapest, Hungary.
Réka Rokonay1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Beáta SzebeniELKH-SE Pediatrics and Nephrology Research Group, Budapest, Hungary.
Gábor Lotz2nd Department of Pathology, Semmelweis University, Budapest, Hungary.
Nóra J Béres1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Áron Cseh1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Attila J Szabó1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary.
Ádám Vannay1st Department of Pediatrics, Semmelweis University, 54, Bókay Street, Budapest, 1083, Hungary. vannay.adam@med.semmelweis-univ.hu.
Semmelweis University · HUTokyo University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently the role of Parkinson's disease 7 (PARK7) was studied in gastrointestinal diseases, however, the complex role of PARK7 in the intestinal inflammation is still not completely clear. Expression and localization of PARK7 were determined in the colon biopsies of children with inflammatory bowel disease (IBD), in the colon of dextran sodium sulphate (DSS) treated mice and in HT-29 colonic epithelial cells treated with interleukin (IL)-17, hydrogen peroxide (H

Indexed as

AdolescentAnimalsChildChild, PreschoolColitisColonCytokinesDisease Models, AnimalEpithelial CellsFemaleGene Expression RegulationHT29 CellsHumansHydrogen PeroxideInfantInflammatory Bowel DiseasesCytokinesHydrogen PeroxidePARK7 protein, humanProtein Deglycase DJ-1

Identifiers

PMID34272410
PMCPMC8285373
OpenAlexW3177833270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.