ReviewCritical care (London, England)2021
Personalized mechanical ventilation in acute respiratory distress syndrome.
Review in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05566652 (Neural Pressure Support for Low Pulmonary Compliance), which is not on this map. Cited by 111 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neural Pressure Support for Low Pulmonary Compliance
Who cites it
111 citing papers in PubMed, 3 syntheses or guidelines pooled it, 200 citations in OpenAlex.
- Electrical impedance tomography-guided positive end-expiratory pressure titration in ARDS: a systematic review and meta-analysis.Intensive care medicine · 2024Pooled it
- Emerging roles of mechanosensitive ion channels in ventilator induced lung injury: a systematic review.Frontiers in immunology · 2024Pooled it
- Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome: a systematic review and meta-analysis.The Lancet. Respiratory medicine · 2022Pooled it
- Respiratory effects of recruitment maneuvers according to lung recruitability assessed by electrical impedance tomography in patients with acute respiratory distress syndrome.Journal of clinical monitoring and computing · 2026Trial
- Individualized Lung-Protective Ventilation Strategy Based on Esophageal Pressure Monitoring in Patients With ARDS Associated With Severe Acute Pancreatitis-A Randomized Controlled Trial.World journal of surgery · 2025Trial
- Distribution of airway pressure opening in the lungs measured with electrical impedance tomography (POET): a prospective physiological study.Critical care (London, England) · 2025Trial
- Effects of non-invasive respiratory supports on inspiratory effort in moderate-severe COVID-19 patients. A randomized physiological study.European journal of internal medicine · 2022Trial
- Predicting global and regional respiratory response in ARDS patients through individualized physics-based computational lung models: a prospective clinical pilot study.Respiratory research · 2026Article
- Physiology-guided mechanical ventilation: Monitoring, proportional assist, and bounded automation.World journal of critical care medicine · 2026Review
- Mechanical Power as a Predictor of Outcomes During Mechanical Ventilation in Coronavirus Disease 2019 (COVID-19): An Updated Systematic Review.Journal of clinical medicine · 2026Review
- Beyond admission day: operative intent and physiological readiness in rapid chest wall reconstruction.Critical care (London, England) · 2026Article
- CARE-ATLANTIC: understanding cross cultural differences in goals of care; a transatlantic study in critical care medicine.BMC medical ethics · 2026Article
- Right ventricular-protective ventilation in acute respiratory distress syndrome: phenotypes, monitoring and ventilatory management.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Ultra-low versus low tidal volume ventilation in acute respiratory distress syndrome: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- Deep knowledge-driven multi-modal fusion for diagnosis and prognosis of SI-ARDS.Communications medicine · 2026Article
- Targeting driving pressure in ARDS: refining the "When" and "How" after the STAMINA trial.Journal of thoracic disease · 2026Article
- Article
- Unbiased characterization of COVID-19 endotypes leads to prognostication of high-risk individuals using routine blood tests.Communications medicine · 2026Article
- Beyond One-Size-Fits-All: Precision Mechanical Ventilation in ARDS.Journal of clinical medicine · 2026Review
- Mechanical ventilation in ARDS: navigating the fine line with real-time monitoring.Critical care (London, England) · 2026Review
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 13 institutions in 13 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A personalized mechanical ventilation approach for patients with adult respiratory distress syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging, and biological phenotypes may improve ventilation practice and outcome. However, additional research is warranted before personalized mechanical ventilation strategies can be applied at the bedside. Ventilatory parameters should be titrated based on close monitoring of targeted physiologic variables and individualized goals. Although low tidal volume (V
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.