ArticleNutrition journal2021
Dietary intake of fatty acids and risk of pancreatic cancer: Golestan cohort study.
Article in Nutrition journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Pooled it
- Association of saturated fatty acids with cancer risk: a systematic review and meta-analysis.Lipids in health and disease · 2024Pooled it
- Dietary fatty acid intake and the risk of pancreatic cancer: a dose-response meta-analysis of observational studies.Annals of medicine and surgery (2012) · 2026Article
- Effects of Proglumide with Chemotherapy on the Pancreatic Tumor Microenvironment: Phase 1 PROGEM Trial.Pharmaceutics · 2026Article
- Association of fat quality index with head and neck cancer risk: results from a prospective study.Frontiers in nutrition · 2026Article
- Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer.BMC medicine · 2025Article
- Pan-cancer analysis of the impact of fatty acids: a two-sample and multivariable Mendelian randomization study.Discover oncology · 2025Article
- Examining the dietary contributions of lipids to pancreatic cancer burden (1990-2021): incidence trends and future projections.Lipids in health and disease · 2025Article
- Dietary nutrient intake and cancer presence: evidence from a cross-sectional study.Frontiers in nutrition · 2025Article
- Pasta Incorporating Olive Pomace: Impact on Nutritional Composition and Consumer Acceptance of a Prototype.Foods (Basel, Switzerland) · 2024Article
- Adherence to a Cholesterol-Lowering Diet and the Risk of Pancreatic Cancer: A Case-Control Study.Nutrients · 2024Article
- Prospective Study of Avocado Consumption and Cancer Risk in U.S. Men and Women.Cancer prevention research (Philadelphia, Pa.) · 2023Article
- What Dietary Patterns and Nutrients are Associated with Pancreatic Cancer? Literature Review.Cancer management and research · 2023Review
- Potential Therapeutic Properties of the Leaf ofPlants (Basel, Switzerland) · 2022Article
- Dietary Intake of Fatty Acids and Risk of Pancreatic Cancer: A Case-Control Study.The Journal of nutrition · 2022Article
- Fried food consumption and the risk of pancreatic cancer: A large prospective multicenter study.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs pancreatic cancer (PC) is a malignancy with poor prognosis, finding strategies for its prevention became a notable priority. Among all the factors influencing the risk of PC, dietary items especially fats are considered as the most modifiable risk factors.This study is designed to assess the associations of dietary intake of fatty acids with the risk of PC incidence.
methodsA total of 50,045 adults between 40 and 75 years old participated in this cohort study in 2004-2008 and were followed up to the present. Intakes of fatty acids was evaluated by validated food-frequency questionnaire (FFQ). Cox proportional hazards regression model was used to estimate hazard ratio (HR) with 95 % confidence interval of differing levels of dietary intakes of fatty acids for incidence of PC.
resultsAt the end of follow-up period, 76 cases of PC were identified and 46,904 participants without history of cancer, acute kidney disorders, fibrosis and cirrhosis were included in the study. Dietary total saturated fatty acids (SFAS) was associated with PC risk (HR = 1.05 (1.01-1.09), P
conclusionsThe amount of total fat intake is not a risk factor for PC in our study and focusing on the intake of specific fatty acids becomes more striking. Unsaturated fatty acids including PUFAS and especially MUFAS are considered as protective dietary factors in PC prevention. In contrast, total SFAS is positively associated with the increased risk of PC. However, very long chain and odd-chain saturated fatty acids intake may be protective against PC.
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