Evidence map›Paper›PMID 34271558›Full record

ArticlePhysics in medicine and biology2021

Full field-of-view, high-resolution, photon-counting detector CT: technical assessment and initial patient experience.

Kishore Rajendran, Martin Petersilka, André Henning, Elisabeth Shanblatt, Jeffrey Marsh, Jamison Thorne, Bernhard Schmidt, Thomas Flohr, Joel Fletcher, Cynthia McCollough and 1 more

Open access · greenAbstract read
In one paragraph

Article in Physics in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 117 citations in OpenAlex.

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  18. New imaging techniques and trends in radiology.Diagnostic and interventional radiology (Ankara, Turkey) · 2025
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Kishore RajendranDepartment of Radiology, Mayo Clinic, Rochester, MN, United States of America.ORCID 0000-0002-8314-3642
Martin PetersilkaSiemens Healthineers GmbH, Forchheim, Germany.
André HenningSiemens Healthineers GmbH, Forchheim, Germany.
Elisabeth ShanblattSiemens Medical Solutions, Malvern, PA, United States of America.
Jeffrey MarshDepartment of Radiology, Mayo Clinic, Rochester, MN, United States of America.
Jamison ThorneDepartment of Radiology, Mayo Clinic, Rochester, MN, United States of America.
Bernhard SchmidtSiemens Healthineers GmbH, Forchheim, Germany.
Thomas FlohrSiemens Healthineers GmbH, Forchheim, Germany.
Joel FletcherDepartment of Radiology, Mayo Clinic, Rochester, MN, United States of America.
Cynthia McColloughDepartment of Radiology, Mayo Clinic, Rochester, MN, United States of America.
Shuai LengDepartment of Radiology, Mayo Clinic, Rochester, MN, United States of America.
Mayo Clinic in Florida · USSiemens Healthineers (Germany) · DE

Funding

Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementR01EB028590 · NIBIB · MAYO CLINIC ROCHESTER · PI LENG, SHUAI, MCCOLLOUGH, CYNTHIA H · 2020 to 2023
$2.6M
EXTRAMURAL RES FACIL IMPROVEMENT PROG: POLYCYSTIC KIDNEY DISEASE, RENAL STUDIES,C06RR018898 · NCRR · MAYO CLINIC · PI BURNETT, JOHN C · 2004 to 2004
$2.3M
NCRR NIH HHS C06 RR018898NIBIB NIH HHS R01 EB028590
6 · The paper itself

Abstract

We report a comprehensive evaluation of a full field-of-view (FOV) photon-counting detector (PCD) computed tomography (CT) system using phantoms, and qualitatively assess image quality in patient examples. A whole-body PCD-CT system with 50 cm FOV, 5.76 cm z-detector coverage and two acquisition modes (standard: 144 × 0.4 mm collimation and ultra-high resolution (UHR): 120 × 0.2 mm collimation) was used in this study. Phantoms were scanned to assess image uniformity, CT number accuracy, noise power spectrum, spatial resolution, material decomposition and virtual monoenergetic imaging (VMI) performance. Four patients were scanned on the PCD-CT system with matched or lower radiation dose than their prior clinical CT scans performed using energy-integrating detector (EID) CT, and the potential clinical impact of PCD-CT was qualitatively evaluated. Phantom results showed water CT numbers within ±5 HU, and image uniformity measured between peripheral and central regions-of-interests to be within ±5 HU. For the UHR mode using a dedicated sharp kernel, the cut-off spatial frequency was 40 line-pairs cm

Indexed as

IodinePhotonsHumansPatient Outcome AssessmentPhantoms, ImagingTomography, X-Ray ComputedIodineimage analysisphoton-counting detectorspatial resolutionx-ray computed tomography

Identifiers

PMID34271558
PMCPMC8551012
OpenAlexW3181148466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.