Observational studyJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2021
Acute Central Retinal Artery Occlusion Seen within 24 Hours at a Tertiary Institution.
Observational study in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- The Effects of Hyperbaric Oxygen Therapy in Patients with Central Retinal Artery Occlusion: A Retrospective Study, Systematic Review, and Meta-analysis.Korean journal of ophthalmology : KJO · 2022Pooled it
- Global research trends in central retinal artery occlusion: a bibliometric analysis (1980-2025).International ophthalmology · 2026Review
- Impact of an eye-stroke protocol with non-mydriatic ocular imaging in an emergency department.Frontiers in neurology · 2026Article
- Effectiveness and safety of superselective ophthalmic artery thrombolysis beyond 24h in central retinal artery occlusion.International journal of ophthalmology · 2026Article
- Central Retinal Artery Occlusion in Acute Care: Current Practices and Emerging Therapies.Cureus · 2025Review
- Artificial Intelligence-Based Detection of Central Retinal Artery Occlusion Within 4.5 Hours on Standard Fundus Photographs.Journal of the American Heart Association · 2025Observational
- Retinal Artery Occlusion: A Review of Current Management Practices.Journal of ophthalmic & vision research · 2024Review
- Central retinal artery occlusion: a stroke of the eye.Eye (London, England) · 2024Review
- Implementation of a retinal stroke-code protocol results in visual recovery in patients receiving reperfusion therapies.European stroke journal · 2024Article
- Central Retinal Artery Occlusion: A Review of Pathophysiological Features and Management.Stroke (Hoboken, N.J.) · 2024Review
- Relation between peripheral blood inflammatory indices and severity of central retinal artery occlusion.PeerJ · 2024Article
- Thrombolytic Therapy for Central Retinal Artery Occlusion in an Academic Multi-Site Stroke Centre.Neuro-ophthalmology (Aeolus Press) · 2024Article
- Central retinal artery occlusion - detection score.Frontiers in medicine · 2023Article
- Risk Factors and Treatment Strategy for Retinal Vascular Occlusive Diseases.Journal of clinical medicine · 2022Review
- Retinal and optic nerve magnetic resonance diffusion-weighted imaging in acute non-arteritic central retinal artery occlusion.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Article
- Current diagnosis and treatment practice of central retinal artery occlusion: results from a survey among German stroke units.Neurological research and practice · 2022Article
- Diagnostic Error in Neuro-ophthalmology: Avenues to Improve.Current neurology and neuroscience reports · 2022Review
- Inner Retinal Layer Hyperreflectivity Is an Early Biomarker for Acute Central Retinal Artery Occlusion.Frontiers in medicine · 2022Article
- Retinal layer reflectivity and thickness as OCT biomarkers for diagnosis and imaging-based stratification relative to the 4.5-h window in acute central retinal artery occlusion.Frontiers in neurologyArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveAcute central retinal artery occlusion (CRAO) is an emergency with poor visual outcome. Intravenous thrombolysis within 4.5 h of vision loss is safe and may improve vision, but is rarely administered because of frequent delays in presentation. We describe a subgroup of CRAO patients presenting within 24 h of vision loss to a tertiary care center affiliated with a comprehensive stroke center. MATERIALS AND
methodsRetrospective review of 181 consecutive CRAO patients seen at our institution from 2010 to 2020.
resultsOut of 181 CRAO patients, 62 (34%) presented within 24 h of vision loss and tended to live closer to the hospital. These patients were more likely to be admitted to the hospital and receive comprehensive stroke work-up compared to patients who presented after 24 h of vision loss. Patients presenting after 24 h did not necessarily receive prior appropriate work-up at outside institutions. Conservative treatments for CRAO were administered to 20/181 patients, and only 3 patients received intravenous thrombolysis.
conclusionsPatients with CRAO do not present to the emergency department fast enough and diagnosis of CRAO is often delayed. Despite having a protocol in place, only 3/181 patients received IV thrombolysis, emphasizing the difficulty in administering very acute treatments for CRAO. Public education regarding CRAO is necessary to improve presentation times, management, and visual outcomes. Hospitals need to develop accelerated diagnostic pathway protocols for patients with acute vision loss so that CRAO patients may be diagnosed and be considered for potential acute treatments as quickly as possible.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.