Evidence map›Paper›PMID 34271175›Full record

ArticleContemporary clinical trials2021

Pragmatic clinic randomized trial to improve chronic kidney disease care: Design and adaptation due to COVID disruptions.

JoAnn M Sperl-Hillen, A Lauren Crain, Lilian Chumba, Heidi L Ekstrom, Deepika Appana, Kristen M Kopski, James B Wetmore, James Wheeler, Areef Ishani, Patrick J O'Connor

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

JoAnn M Sperl-HillenHealthPartners Institute, Minneapolis, MN, United States of America. Electronic address: joann.m.sperlhillen@ghealthpartners.com.
A Lauren CrainHealthPartners Institute, Minneapolis, MN, United States of America.
Lilian ChumbaHealthPartners Institute, Minneapolis, MN, United States of America.
Heidi L EkstromHealthPartners Institute, Minneapolis, MN, United States of America.
Deepika AppanaHealthPartners Institute, Minneapolis, MN, United States of America.
Kristen M KopskiPark Nicollet Medical Group, Minneapolis, MN, United States of America.
James B WetmoreDivision of Nephrology, Hennepin County Medical Center, Minneapolis, MN, United States of America.
James WheelerPark Nicollet Medical Group, Minneapolis, MN, United States of America.
Areef IshaniMinneapolis Veterans Affairs Health Care System and the University of Minnesota, Minneapolis, MN, United States of America.
Patrick J O'ConnorHealthPartners Institute, Minneapolis, MN, United States of America.

Funding

A Technology-Driven Intervention to Improve Identification and Management of Chronic Kidney Disease in Primary CareR18DK118463 · NIDDK · HEALTHPARTNERS INSTITUTE · PI SPERL-HILLEN, JOANN M · 2018 to 2020
$1.5M
NIDDK NIH HHS R18 DK118463
6 · The paper itself

Abstract

backgroundWe describe a clinic-randomized trial to improve chronic kidney disease (CKD) care through a CKD-clinical decision support (CKD-CDS) intervention in primary care clinics and the challenges we encountered due to COVID-19 care disruption. METHODS/

designPrimary care clinics (N = 32) were randomized to usual care (UC) or to CKD-CDS. Between April 17, 2019 and March 14, 2020, more than 7000 patients had accrued for analysis by meeting study-eligibility criteria at an index office visit: age 18-75, laboratory criteria for stage 3 or 4 CKD (eGFR 15-59 mL/min/1.73 m DISCUSSION: We describe a NIH-funded pragmatic trial of web-based EHR-integrated CKD-CDS and modifications necessary mid-study to complete the study as intended in the face of COVID-19 pandemic challenges.

Indexed as

COVID-19Renal Insufficiency, ChronicAdolescentAdultAgedAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsHumansMiddle AgedPandemicsPragmatic Clinical Trials as TopicPrimary Health CareRandomized Controlled Trials as TopicSARS-CoV-2Young AdultAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsChronic kidney diseaseClinical decision supportCOVID care disruptionPragmatic clinical trialPrimary care

Identifiers

PMID34271175
PMCPMC8276567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.