Evidence map›Paper›PMID 34270582›Full record

ArticlePloS one2021

Where will it end? Pathways to care and catastrophic costs following negative TB evaluation in Uganda.

Thomas H A Samuels, Priya B Shete, Chris Ojok, Talemwa Nalugwa, Katherine Farr, Stavia Turyahabwe, Achilles Katamba, Adithya Cattamanchi, David A J Moore

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Thomas H A SamuelsLondon School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID 0000-0002-6177-2165
Priya B SheteUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Chris OjokUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Talemwa NalugwaUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Katherine FarrUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Stavia TuryahabweUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Achilles KatambaUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.
Adithya CattamanchiUganda Tuberculosis Implementation Research Consortium, Kampala, Uganda.ORCID 0000-0002-6553-2601
David A J MooreLondon School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID 0000-0002-3748-0154
University of California, San Francisco · USUniversity College London Hospitals NHS Foundation Trust · GBJohns Hopkins University · USMakerere University · UGMinistry of Health · UG

Funding

SIngle-saMPLE tuberculosis evaluation to facilitate linkage to care: The SIMPLE TB trialR01HL130192 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CATTAMANCHI, ADITHYA · 2016 to 2020
$3.2M
Medical Research Council MR/M017362/1NHLBI NIH HHS R01 HL130192
6 · The paper itself

Abstract

introductionCatastrophic costs incurred by tuberculosis (TB) patients have received considerable attention, however little is known about costs and pathways to care after a negative TB evaluation. MATERIALS AND

methodsWe conducted a cross-sectional study of 70 patients with a negative TB evaluation at four community health centres in rural and peri-urban Uganda. Patients were traced 9 months post-evaluation using contact information from TB registers. We collected information on healthcare visits and implemented locally-validated costing questionnaires to assess the financial impact of their symptoms post-evaluation.

resultsOf 70 participants, 57 (81%) were traced and 53 completed the survey. 31/53 (58%) surveyed participants returned to healthcare facilities post-evaluation, making a median of 2 visits each (interquartile range [IQR] 1-3). 11.3% (95%CI 4.3-23.0%) of surveyed patients and 16.1% (95%CI 5.5-33.7%) of those returning to healthcare facilities incurred catastrophic costs (i.e., spent >20% annual household income). Indirect costs related to lost work represented 80% (IQR 32-100%) of total participant costs.

conclusionsPatients with TB symptoms who experience financial catastrophe after negative TB evaluation may represent a larger absolute number of patients than those suffering from costs due to TB. They may not be captured by existing definitions of non-TB catastrophic health expenditure.

Indexed as

Cost of IllnessAdultFemaleHealth EquityHumansMaleMiddle AgedOffice VisitsTuberculosisUganda

Identifiers

PMID34270582
PMCPMC8284677
OpenAlexW3181065098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.