Evidence map›Paper›PMID 34270366›Full record

SynthesisHuman vaccines & immunotherapeutics2021

Immunogenicity and safety of Ebola virus vaccines in healthy adults: a systematic review and network meta-analysis.

Alhassane Diallo, Miguel Carlos-Bolumbu, Minerva Cervantes-Gonzalez, Veronika Wozniak, Mamadou Hassimiou Diallo, Boubacar Djelo Diallo, Alexandre Delamou, Florence Galtier

Open access · bronzeAbstract readSystematic ReviewNetwork Meta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Alhassane DialloCIC-EC 1425, Department of Epidemiology, Biostatistics, Clinical Research, AP-HP Hospital Bichat, University of Paris Diderot, Paris, France.ORCID 0000-0002-1666-8641
Miguel Carlos-BolumbuDépartement d'Urgence-Réanimation, Centre Hospitalier Sud-Essones CHSE, Paris, France.
Minerva Cervantes-GonzalezCIC-EC 1425, Department of Epidemiology, Biostatistics, Clinical Research, AP-HP Hospital Bichat, Paris, France.
Veronika WozniakFaculty of Medicine, University Paris Diderot, Paris, France.
Mamadou Hassimiou DialloCentre population et développement, Institut de recherche pour le développement, Université Paris Descartes, Paris, France.
Boubacar Djelo DialloFaculté des Sciences et Techniques de la Santé, Université Gamal Abdel Nasser de Conakry, Service de Pneumo-Phtisiologie, CHU Conakry, Hôpital National Ignace Deen de Conakry, Conakry, Guinea.
Alexandre DelamouGamal Abdel Nasser University, Conakry, Guinea.
Florence GaltierINSERM, CIC 1411, CHU of Montpellier, Saint Eloi Hospital, Montpellier, France.
Délégation Paris 7 · FRGamal Abdel Nasser University of Conakry · GNAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Sud-Essonne Dourdan-Etampes · FRInserm · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical development of Ebola virus vaccines (EVV) was accelerated by the West African Ebola virus epidemic which remains the deadliest in history. To compare and rank the EVV according to their immunogenicity and safety. A total of 21 randomized controlled trial, evaluating seven different vaccines with different doses, and 5,275 participants were analyzed. The rVSVΔG-ZEBOV-GP (2 × 10

Indexed as

Ebola VaccinesEbolavirusHemorrhagic Fever, EbolaAdultAntibodies, ViralHumansRandomized Controlled Trials as TopicAntibodies, ViralEbola VaccinesEbolavirushealthy volunteernetwork meta-analysisvaccine

Identifiers

PMID34270366
PMCPMC8437548
OpenAlexW3179275466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.