Evidence map›Paper›PMID 34270094›Full record

Trial reportJournal of medical virology2021

Safety of COVID-19 vaccines.

Qutaiba A Al Khames Aga, Waseem H Alkhaffaf, Tagreed H Hatem, Kawthar F Nassir, Yazan Batineh, Abdullah T Dahham, Dimah Shaban, Luma A Al Khames Aga, Manhal Y R Agha, Muaamar Traqchi

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 11 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 11 syntheses or guidelines pooled it, 185 citations in OpenAlex.

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  13. Safety of COVID-19 vaccines.Journal of medical virology · 2021
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Qutaiba A Al Khames AgaDepartment of Clinical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan.ORCID https://orcid.org/0000-0002-1165-008X
Waseem H AlkhaffafDepartment of Medicine, Faculty of Medicine, Ninevah University, Mosul, Iraq.
Tagreed H HatemDepartment of Gynecology, Bagdad Teaching Hospital, Medical City, Baghdad, Iraq.
Kawthar F NassirDepartment of Gynecology, Bagdad Teaching Hospital, Medical City, Baghdad, Iraq.
Yazan BatinehDepartment of Clinical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan.
Abdullah T DahhamDepartment of Clinical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan.
Dimah ShabanDepartment of Clinical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan.
Luma A Al Khames AgaCOVID-19 Testing Specialist Atechy Group Cardiff, Wales, UK.
Manhal Y R AghaDepartment of Orthopedic Cardiff, University Hospital of Wales, Wales, UK.
Muaamar TraqchiDepartment of Clinical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan.
Philadelphia University · JOBaghdad Medical City · IQUniversity Hospital of Wales · GBUniversity of Mosul · IQUniversity of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is aimed to identify the adverse effects associated with three types of coronavirus disease 2019 vaccines. Approximately 1736 individuals agreed to participate in this study. The participants involved in the study were individuals who had received the first dose or full course (two doses) of the vaccine at least 30 days before the survey. A direct and interactive web-based system interview with a paper and electronic version of the questionnaire was used for all participants. A total of 1736 randomized individuals were identified. The reactogenicity of the vaccines including pain, redness, urticaria, and swelling at the site of the injection was reported in 34.56% of the participants. Local site reaction was reported in more individuals who had Pfizer and AstraZeneca vaccines than those who received the Sinopharm vaccine. The systemic events were more common with AstraZeneca and Pfizer vaccines, symptoms reported were fatigue, body pain, headache, muscle pain, fever, and gastrointestinal side effects. There were no correlations between age or gender, and the duration of the adverse effects for the three vaccines. Swelling and severe allergic reaction of the eyelids, severe hypotension, generalized body aches, shortness of breath, weakness and numbness on the injected arm, acute hyperglycemia, severe chest pain, and fever more than 39°C were among the unusual signs and symptoms reported by the participants. Pfizer, AstraZeneca, and Sinopharm vaccines were found to be safe and Sinopharm vaccine showed a lower prevalence of adverse effects compared with the other vaccines. The duration and severity of adverse effects were not affected by age or gender. Unusual side effects should be closely monitored to establish determine they are linked to the immunization.

Indexed as

AdolescentAdultAgedAged, 80 and overBNT162 VaccineChAdOx1 nCoV-19COVID-19COVID-19 VaccinesFatigueFemaleHeadacheHumansInjection Site ReactionMaleMiddle AgedMyalgiaBNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesAstraZeneca vaccineCOVID-19Pfizer vaccineSinopharm vaccinevaccine

Identifiers

PMID34270094
PMCPMC8426829
OpenAlexW3182716729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.