Evidence map›Paper›PMID 34269968›Full record

ArticleInternational urology and nephrology2021

Cystatin C predicts renal function impairment after partial or radical tumor nephrectomy.

Mike Wenzel, Hang Yu, Annemarie Uhlig, Christoph Würnschimmel, Manuel Wallbach, Andreas Becker, Margit Fisch, Felix K H Chun, Christian P Meyer, Marianne Leitsmann

Open access · hybridAbstract read
In one paragraph

Article in International urology and nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Acute kidney injury in urological conditions.Asian biomedicine : research, reviews and news · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Role of cystatin C in urogenital malignancy.Frontiers in endocrinology · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mike WenzelDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany. Mike.Wenzel@kgu.de.ORCID http://orcid.org/0000-0002-4338-0889
Hang YuDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Annemarie UhligDepartment of Urology, University Medical Center Göttingen, Göttingen, Germany.
Christoph WürnschimmelCancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, QC, Canada.
Manuel WallbachDepartment of Nephrology, University Medical Center Göttingen, Göttingen, Germany.
Andreas BeckerDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.
Margit FischDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Felix K H ChunDepartment of Urology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany.
Christian P MeyerDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marianne LeitsmannDepartment of Urology, University Medical Center Göttingen, Göttingen, Germany.
Universität Hamburg · DEGoethe University Frankfurt · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo test the value of preoperative and postoperative cystatin C (CysC) as a predictor on kidney function after partial (PN) or radical nephrectomy (RN) in renal cell carcinoma (RCC) patients with normal preoperative renal function.

methodsFrom 01/2011 to 12/2014, 195 consecutive RCC patients with a preoperative estimated glomerular filtration rate (eGFR) > 60 ml/min/1.73m

resultsOf 195 patients, 129 (66.2%) underwent PN. In postoperative and in follow-up setting (median 14 months, IQR 10-20), rates of eGFR < 60 ml/min/1.73m

conclusionPreoperative CysC predicts renal function impairment following RCC surgery. Furthermore, CysC might be superior to creatinine for renal function monitoring in the early postoperative setting.

Indexed as

AgedCarcinoma, Renal CellCystatin CFemaleHumansKidney DiseasesKidney NeoplasmsMaleMiddle AgedNephrectomyPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesCystatin CAcute kidney injuryCystatin CGFRNephrectomyRenal cell carcinoma

Identifiers

PMID34269968
PMCPMC8463386
OpenAlexW3179797528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.