Evidence map›Paper›PMID 34269905›Full record

ReviewCurrent rheumatology reports2021

Imaging of Joint and Soft Tissue Involvement in Systemic Lupus Erythematosus.

Andrea Di Matteo, Gianluca Smerilli, Edoardo Cipolletta, Fausto Salaffi, Rossella De Angelis, Marco Di Carlo, Emilio Filippucci, Walter Grassi

Open access · hybridAbstract readReview
In one paragraph

Review in Current rheumatology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Dual seropositive nonerosive lupus arthritis: rhupus or not?Advances in rheumatology (London, England) · 2025
    Article
  10. Article
  11. Pivotal role of the synovioentheseal complex in the imaging of arthritis and rheumatic diseasesDiagnostic and interventional radiology (Ankara, Turkey) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Andrea Di MatteoPolytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy. andrea.dimatteo@hotmail.com.ORCID 0000-0003-0867-7051
Gianluca SmerilliPolytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Edoardo CipollettaPolytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Fausto SalaffiPolytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Rossella De AngelisPolytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Marco Di CarloPolytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Emilio Filippucci *Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Walter Grassi *Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Via Aldo Moro 25, 60035 Jesi, Ancona, Italy.
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo highlight the potential uses and applications of imaging in the assessment of the most common and relevant musculoskeletal (MSK) manifestations in systemic lupus erythematosus (SLE). RECENT

findingsUltrasound (US) and magnetic resonance imaging (MRI) are accurate and sensitive in the assessment of inflammation and structural damage at the joint and soft tissue structures in patients with SLE. The US is particularly helpful for the detection of joint and/or tendon inflammation in patients with arthralgia but without clinical synovitis, and for the early identification of bone erosions. MRI plays a key role in the early diagnosis of osteonecrosis and in the assessment of muscle involvement (i.e., myositis and myopathy). Conventional radiography (CR) remains the traditional gold standard for the evaluation of structural damage in patients with joint involvement, and for the study of bone pathology. The diagnostic value of CR is affected by the poor sensitivity in demonstrating early structural changes at joint and soft tissue level. Computed tomography allows a detailed evaluation of bone damage. However, the inability to distinguish different soft tissues and the need for ionizing radiation limit its use to selected clinical circumstances. Nuclear imaging techniques are valuable resources in patients with suspected bone infection (i.e., osteomyelitis), especially when MRI is contraindicated. Finally, dual energy X-ray absorptiometry represents the imaging mainstay for the assessment and monitoring of bone status in patients with or at-risk of osteoporosis. Imaging provides relevant and valuable information in the assessment of MSK involvement in SLE.

Indexed as

Lupus Erythematosus, SystemicSynovitisHumansMagnetic Resonance ImagingTendonsUltrasonographyComputed tomography (CT)Conventional radiography (CR)ImagingMagnetic resonance imaging (MRI)Musculoskeletal involvementSystemic lupus erythematosusultrasound (US)

Identifiers

PMID34269905
PMCPMC8285327
OpenAlexW3178843096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.