SynthesisPediatric surgery international2021
Laparoscopic vs open portoenterostomy in biliary atresia: a systematic review and meta-analysis.
Synthesis in Pediatric surgery international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Comparison of different Kasai portoenterostomy techniques in the outcomes of biliary atresia: a systematic review and network meta-analysis.Pediatric surgery international · 2024Pooled it
- Laparoscopic versus open Kasai procedure for biliary atresia: long-term results of a randomized clinical trial.Pediatric surgery international · 2023Trial
- Comparative outcomes of open and laparoscopic Kasai portoenterostomy for biliary Atresia patients progressing to liver transplantation: A Real-World cohort study.Surgery today · 2026Article
- Obstruction of the Biliary Limb of the Roux Loop After Successful Kasai Portoenterostomy for Biliary Atresia: Report of Two Cases.The American journal of case reports · 2026Article
- Comparison of surgical results and technical performance between robotic and laparoscopic approaches for Kasai portoenterostomy in biliary atresia: a multicenter retrospective study.Surgical endoscopy · 2025Article
- Comparison between robotic-assisted Kasai portoenterostomy and open Kasai portoenterostomy in patients with biliary atresia.Surgical endoscopy · 2025Article
- Laparoscopic Kasai portoenterostomy for biliary atresia: first experience from Central Asia.Frontiers in pediatrics · 2025Article
- Cholestasis after Kasai operation predicts portal hypertension in native liver survivors of biliary atresia: a multicenter study.Pediatric surgery international · 2024Article
- Robotic-assisted Kasai portoenterostomy for biliary atresia.Surgical endoscopy · 2023Article
- Peri-Operative Liver Fibrosis and Native Liver Survival in Pediatric Patients with Biliary Atresia: A Systematic Review and Meta-Analysis.Pediatric gastroenterology, hepatology & nutrition · 2022Review
- Response to: Letter to the Editor, Minimally Invasive versus Open Surgery for Spinal Metastasis: A Systematic Review and Meta-Analysis.Asian spine journal · 2021Article
- Extended Adhesion-Sparing Liver Eversion during Kasai Portoenterostomy for Infants with Biliary Atresia.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatoportoenterostomy remains the cornerstone of treatment for biliary atresia. Current employed techniques include laparoscopy and open surgery. This study aims to determine if either method provides an advantage. Following PRISMA guidelines, a systematic review was conducted. Nineteen studies were included. Mean operative time 34.98 (95% CI 20.10, 49.85; p ≤ 0.00001) was longer in laparoscopic while bleeding volumes - 16.63 (95% CI - 23.39, - 9.86; p ≤ 0.00001) as well as the time to normal diet - 2.42 (95% CI - 4.51, - 0.32; p = 0.02) were lower in the laparoscopic group. No differences were observed in mean length of stay - 0.83. Similar complication, transfusions, postoperative cholangitis 0.97, and transplant free survival rates 1.00 (0.63, 1.60; p = 0.99) were seen between groups. Laparoscopic portoenterostomy provides advantages on operative time and bleeding as well as to normal diet when compared to open procedures. Both procedures showed no differences in length of stay, complications, cholangitis, and importantly, native liver survival. Level of evidence: III.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.