ArticleSurgery today2022
The survival after recurrence of colorectal cancer: a retrospective study focused on time to recurrence after curative resection.
Article in Surgery today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Prognostic Factors for Cancer-Specific Survival after Recurrence in Chemo-Naïve Stage I-III Colorectal Cancer.Journal of gastrointestinal cancer · 2026Article
- Perineural invasion as an independent predictor of early recurrence within 1 year after total mesorectal excision for rectal cancer.World journal of surgical oncology · 2026Article
- Article
- AAbdominal radiology (New York) · 2025Article
- Diagnostic Performance of F-18 FDG PET/CT in the Detection of Recurrent Colorectal Cancer: Correlation with Biochemical Markers and Conventional Imaging Modalities.Journal of clinical medicine · 2024Article
- Age-related differences in progression patterns, follow-up strategies, and postoperative outcomes in locally advanced rectal cancer: insights from a large-scale validated study.Therapeutic advances in medical oncology · 2024Article
- Early recurrence after complete mesocolic excision for right-sided colon cancer with D3 lymphadenectomy: pattern, risk factors, prognostic impact, and individualized follow-up.Updates in surgery · 2024Article
- Article
- Peristomal adenocarcinoma 16 years after colorectal adenocarcinoma resection with curative intent.Journal of surgical case reports · 2023Article
- A refined prediction of early recurrence combining tumor deposits in patients with resected rectal mucinous adenocarcinoma.Surgery today · 2023Article
- Influence of the initial recurrence site on prognosis after radical surgery for colorectal cancer: a retrospective cohort study.World journal of surgical oncology · 2023Article
- The incidence of cancer recurrence and new cancer following commencement of dialysis.Clinical kidney journal · 2022Article
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Authors and funding
15 authors.
Funding
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Abstract
purposeThe significance of the duration of the recurrence-free survival after curative resection for colorectal cancer remains unclear. The purpose was to reveal the association between time to recurrence after surgery and the survival after recurrence.
methodsPatients with stage II and III colorectal cancer who underwent curative resection between 2007 and 2015 were retrospectively reviewed (n = 645). Patients with recurrence after surgery (n = 133) were divided into 2 groups: early recurrence (within 13 months after surgery, n = 63) and late recurrence (more than 13 months after surgery, n = 70). The overall survival after recurrence and clinicopathological features were compared between early recurrence, late recurrence, and without recurrence groups.
resultsThe overall survival after recurrence was significantly shorter in patients with early recurrence occurring at less than 13 months (hazard ratio: 1.70, p = 0.03). A high preoperative CA19-9 level (odds ratio [OR]: 2.38, p = 0.03), venous invasion (OR: 2.26, p = 0.03), and the absence of adjuvant chemotherapy (OR: 2.08, p = 0.04) were independently correlated with early recurrence.
conclusionEarly recurrence was associated with a poor prognosis after recurrence. Venous invasion correlated with early recurrence. Adjuvant chemotherapy may reduce the risk of early recurrence. These results indicate the importance of prudent surveillance and the aggressive application of adjuvant chemotherapy.
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