Evidence map›Paper›PMID 34269610›Full record

ArticleThe American journal of sports medicine2021

Neither Residual Anterior Knee Laxity Up to 6 mm nor a Pivot Glide Predict Patient-Reported Outcome Scores or Subsequent Knee Surgery Between 2 and 6 Years After ACL Reconstruction.

Robert A Magnussen, Emily K Reinke, Laura J Huston, MOON Knee Group, Isaac Briskin, Charles L Cox, Warren R Dunn, David C Flanigan, Morgan H Jones, Christopher C Kaeding and 5 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The American journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. From fracture to joint injury: association between CT-based fracture characteristics and surgically treated non-bony injuries in tibial plateau fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Knee Laxity in the Menstrual Cycle after Anterior Cruciate Ligament Reconstruction: A Case Series.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Robert A MagnussenWexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
Emily K ReinkeSports Medicine, Orthopaedic Surgery Research, Duke University Medical Center, Duke Sports Science Institute, Durham, North Carolina, USA.
Laura J HustonDepartment of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
MOON Knee GroupInvestigation performed at The Ohio State University, Columbus, Ohio, USA; the Vanderbilt University Medical Center, Nashville, Tennessee, USA; and the Cleveland Clinic, Cleveland, Ohio, USA.
Isaac BriskinCleveland Clinic, Cleveland, Ohio, USA.
Charles L CoxVanderbilt University Medical Center, Nashville, Tennessee, USA.
Warren R DunnTexas Orthopedic Hospital, Houston, Texas, USA.
David C FlaniganThe Ohio State University, Columbus, Ohio, USA.
Morgan H JonesCleveland Clinic, Cleveland, Ohio, USA.
Christopher C KaedingThe Ohio State University, Columbus, Ohio, USA.
Matthew J MatavaWashington University, St. Louis, Missouri, USA.
Richard D ParkerCleveland Clinic, Cleveland, Ohio, USA.
Matthew V SmithWashington University, St. Louis, Missouri, USA.
Rick W WrightVanderbilt University Medical Center, Nashville, Tennessee, USA.
Kurt P SpindlerDepartment of Orthopaedics, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Cleveland Clinic · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Prognosis and Predictors of ACL Reconstruction: A Multicenter Cohort StudyR01AR053684 · NIAMS · VANDERBILT UNIVERSITY · PI SPINDLER, KURT PAUL · 2006 to 2020
$8.3M
Meniscus status and activity level after ACLK23AR066133 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI JONES, MORGAN HERANCOURT · 2015 to 2019
$745k
Can Physical Examination predict Patient-Reported Outcomes of ACL Reconstruction?K23AR063767 · NIAMS · OHIO STATE UNIVERSITY · PI MAGNUSSEN, ROBERT ANDREW · 2013 to 2017
$635k
NCATS NIH HHS UL1 TR002243NIAMS NIH HHS K23 AR063767NIAMS NIH HHS K23 AR066133NIAMS NIH HHS R01 AR053684
6 · The paper itself

Abstract

backgroundA primary goal of anterior cruciate ligament reconstruction (ACLR) is to reduce pathologically increased anterior and rotational laxity of the knee, but the effects of residual laxity on patient-reported outcomes (PROs) after ACLR remain unclear. HYPOTHESIS: Increased residual laxity at 2 years postoperatively is predictive of a higher risk of subsequent ipsilateral knee surgery and decreases in PRO scores from 2 to 6 years after surgery. STUDY

designCohort study; Level of evidence, 2.

methodsFrom a prospective multicenter cohort, 433 patients aged <36 years were identified at a minimum 2 years after primary ACLR. These patients underwent a KT-1000 arthrometer assessment and pivot-shift test and completed PRO assessments with the Knee injury and Osteoarthritis Outcome Score and International Knee Documentation Committee (IKDC) scores. Patients completed the same PROs at 6 years postoperatively, and any subsequent ipsilateral knee procedures during this period were recorded. Subsequent surgery risk and change in PROs from 2 to 6 years postoperatively were compared based on residual side-to-side KT-1000 arthrometer differences (<-1 mm, -1 to 2 mm, 2 to 6 mm, and >6 mm) in laxity at 2 years postoperatively. Multiple linear regression models were built to determine the relationship between 2-year postoperative knee laxity and 2- to 6-year change in PROs while controlling for age, sex, body mass index, smoking status, meniscal and cartilage status, and graft type.

resultsA total of 381 patients (87.9%) were available for follow-up 6 years postoperatively. There were no significant differences in risk of subsequent knee surgery based on residual knee laxity. Patients with a difference >6 mm in side-to-side anterior laxity at 2 years postoperatively were noted to have a larger decrease in PROs from 2 to 6 years postoperatively (

conclusionThe presence of a residual side-to-side KT-1000 arthrometer difference <6 mm or pivot glide at 2 years after ACLR is not associated with an increased risk of subsequent ipsilateral knee surgery or decreased PROs up to 6 years after ACLR. Conversely, patients exhibiting a difference >6 mm in side-to-side anterior laxity were noted to have significantly decreased PROs at 6 years after ACLR.

Indexed as

Anterior Cruciate Ligament InjuriesCohort StudiesHumansKnee JointPatient Reported Outcome MeasuresProspective StudiesTreatment Outcomeanterior cruciate ligamentknee laxitypatient-reported outcomesreconstruction

Identifiers

PMID34269610
PMCPMC9202674
OpenAlexW3177753797

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.