Evidence map›Paper›PMID 34269488›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2021

Mechanistic Aspects of the Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling Reaction.

Massimo C D'Alterio, Èric Casals-Cruañas, Nikolaos V Tzouras, Giovanni Talarico, Steven P Nolan, Albert Poater

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Review
  2. Article
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  6. Review
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  9. Article
  10. Review
  11. Analyzing the Solvent Effects in Palladium/The journal of physical chemistry. B · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Transmetalation From Boron to Beryllium in Phosphorus-Based Scorpionate Complexes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Massimo C D'AlterioInstitut de Química Computacional i Catàlisi Departament de Química, Universitat de Girona, c/ Maria Aurèlia Capmany 69, 17003, Girona, Catalonia, Spain.
Èric Casals-CruañasInstitut de Química Computacional i Catàlisi Departament de Química, Universitat de Girona, c/ Maria Aurèlia Capmany 69, 17003, Girona, Catalonia, Spain.
Nikolaos V TzourasDepartment of Chemistry and Center for Sustainable Chemistry, Ghent University, Building S3, Krijgslaan 281, 9000, Gent, Belgium.
Giovanni TalaricoDipartimento di Scienze Chimiche, Università di Napoli, Federico II Via Cintia, I-80126, Napoli, Italy.
Steven P NolanDepartment of Chemistry and Center for Sustainable Chemistry, Ghent University, Building S3, Krijgslaan 281, 9000, Gent, Belgium.ORCID http://orcid.org/0000-0001-9024-2035
Albert PoaterInstitut de Química Computacional i Catàlisi Departament de Química, Universitat de Girona, c/ Maria Aurèlia Capmany 69, 17003, Girona, Catalonia, Spain.ORCID http://orcid.org/0000-0002-8997-2599

Funding

Fonds Wetenschappelijk Onderzoek 11I6921NiBOF C3 projectInstitució Catalana de Recerca i Estudis Avançats ICREA Academia 2019Ministerio de Ciencia, Innovación y Universidades PGC2018-097722-B-I00
6 · The paper itself

Abstract

The story of C-C bond formation includes several reactions, and surely Suzuki-Miyaura is among the most outstanding ones. Herein, a brief historical overview of insights regarding the reaction mechanism is provided. In particular, the formation of the catalytically active species is probably the main concern, thus the preactivation is in competition with, or even assumes the role of the rate determining step (rds) of the overall reaction. Computational chemistry is key in identifying the rds and thus leading to milder conditions on an experimental level by means of predictive catalysis.

Indexed as

PalladiumCatalysisPalladiumC−C bond formationCross couplingDFTpalladiumpreactivationSuzuki-Miyaura

Identifiers

PMID34269488
PMCPMC8518397

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.