Evidence map›Paper›PMID 34269473›Full record

ArticleThe EMBO journal2021

TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans.

Yisui Xia, Ryo Fujisawa, Tom D Deegan, Remi Sonneville, Karim P M Labib

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The TIMELESS effort for timely DNA replication and protection.Cellular and molecular life sciences : CMLS · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Valosin Containing Protein (VCP): A Multistep Regulator of Autophagy.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Coordinating DNA Replication and Mitosis through Ubiquitin/SUMO and CDK1.International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yisui XiaThe MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0002-5576-2147
Ryo FujisawaThe MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0003-1985-1668
Tom D DeeganThe MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0001-9639-7636
Remi SonnevilleThe MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0002-2149-2652
Karim P M LabibThe MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0001-8861-379X
University of Dundee · GB

Funding

Cancer Research UK 24558Cancer Research UK C578/A24558Medical Research Council MC_UU_00018/4Medical Research Council MC_UU_12016/13Wellcome TrustWellcome Trust 204678/Z/16/Z
6 · The paper itself

Abstract

The eukaryotic replisome is rapidly disassembled during DNA replication termination. In metazoa, the cullin-RING ubiquitin ligase CUL-2

Indexed as

DNA ReplicationAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsCullin ProteinsDNA-Directed DNA PolymeraseMultienzyme ComplexesReplisomesSynthetic Lethal MutationsCaenorhabditis elegans ProteinsCarrier ProteinsCullin ProteinsDNA-Directed DNA PolymeraseMultienzyme ComplexesReplisomesTIM-1 protein, C elegansUBXN-3 protein, C elegansCDC-48CMG helicaseCUL-2LRR-1DNA replication terminationTIMELESS-TIPINUBXN-3

Identifiers

PMID34269473
PMCPMC8408604
OpenAlexW3180688762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.