Evidence map›Paper›PMID 34269457›Full record

ArticleTransfusion2021

Effect of parachute delivery on red blood cell (RBC) and plasma quality measures of blood for transfusion.

Mark Bates, Sarah Watts, Heidi Doughty, Tom Woolley, Andrew Miles, Liam Barry, Dominic Jenner, Andrew Sedman, Robert Purcell, Emrys Kirkman

Open access · hybridAbstract read
In one paragraph

Article in Transfusion, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mark BatesCBR Division, Dstl Porton Down, Salisbury, UK.
Sarah WattsCBR Division, Dstl Porton Down, Salisbury, UK.ORCID 0000-0001-7943-0078
Heidi DoughtyNIHR Surgical Reconstruction and Microbiology Research Centre, Institute of Translational Medicine, Birmingham, UK.ORCID 0000-0002-5444-6222
Tom WoolleyAcademic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK.ORCID 0000-0001-9957-6453
Andrew MilesCentre of Defence Pathology, Royal Centre for Defence Medicine, Birmingham, UK.
Liam BarryCentre of Defence Pathology, Royal Centre for Defence Medicine, Birmingham, UK.ORCID 0000-0001-6582-0921
Dominic JennerCBR Division, Dstl Porton Down, Salisbury, UK.ORCID 0000-0003-0549-1753
Andrew SedmanPlatform Systems Division, Dstl Porton Down, Salisbury, UK.
Robert PurcellCBR Division, Dstl Porton Down, Salisbury, UK.ORCID 0000-0003-3295-3298
Emrys KirkmanCBR Division, Dstl Porton Down, Salisbury, UK.ORCID 0000-0002-6398-8349
Defence Science and Technology Laboratory · GBRoyal Navy · GBNHS Blood and Transplant · GB

Funding

NHS Blood and TransplantUK Ministry of Defence as part of the Chief Scientific Advisor Research Programme
6 · The paper itself

Abstract

backgroundParachute airdrop offers a rapid transfusion supply option for humanitarian aid and military support. However, its impact on longer-term RBC survival is undocumented. This study aimed to determine post-drop quality of RBCs in concentrates (RCC), and both RBCs and plasma in whole blood (WB) during subsequent storage. STUDY DESIGN AND

methodsTwenty-two units of leucodepleted RCC in saline, adenine, glucose, mannitol (SAGM) and 22 units of nonclinical issue WB were randomly allocated for air transportation, parachute drop, and subsequent storage (parachute), or simply storage under identical conventional conditions (4 ± 2°C) (control). All blood products were 6-8 days post-donation. Parachute units were packed into Credo Cubes, (Series 4, 16 L) inside a PeliCase (Peli 0350) and rigged as parachute delivery packs. Packs underwent a 4-h tactical flight (C130 aircraft), then parachuted from 250 to 400 ft before ground recovery. The units were sampled aseptically before and after airdrop at weekly intervals. A range of assays quantified the RBC storage lesion and coagulation parameters.

resultsBlood units were maintained at 2-6°C and recovered intact after recorded ground impacts of 341-1038 m s DISCUSSION: Appropriately packaged aerial delivery by parachute can be successfully used for blood supply.

Indexed as

Blood TransfusionPlasmaTransportationBlood PreservationErythrocytesHumansQuality Indicators, Health Careaustere environmentbloodparachuteRBC concentratered blood celltransfusionwhole blood

Identifiers

PMID34269457
PMCPMC9290599
OpenAlexW3179838284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.