Evidence map›Paper›PMID 34269437›Full record

ArticleTransfusion2021

Treating the endotheliopathy of SARS-CoV-2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products.

Shibani Pati, Erin Fennern, John B Holcomb, Mark Barry, Alpa Trivedi, Andrew P Cap, Matthew J Martin, Charles Wade, Rosemary Kozar, Jessica C Cardenas and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Transfusion, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shibani PatiDepartment of Lab Medicine, University of California San Francisco School of Medicine, San Francisco, California, USA.ORCID 0000-0001-8554-4450
Erin FennernDepartment of Surgery, Mount Sinai Icahn School of Medicine, New York, New York, USA.ORCID 0000-0002-7501-3354
John B HolcombUniversity of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-8312-9157
Mark BarryDepartment of Surgery, University of California San Francisco School of Medicine, San Francisco, California, USA.
Alpa TrivediDepartment of Lab Medicine, University of California San Francisco School of Medicine, San Francisco, California, USA.
Andrew P CapU.S. Army Institute of Surgical Research, JBSA-FT Sam Houston, San Antonio, Texas, USA.
Matthew J MartinDepartment of Surgery, Scripps Mercy Hospital, San Diego, California, USA.
Charles WadeDepartment of Surgery McGovern School of Medicine, University of Texas Health Science Center, Houston, Texas, USA.ORCID 0000-0003-0055-5885
Rosemary KozarDepartment of Surgery, University of Maryland, Baltimore, Maryland, USA.
Jessica C CardenasDepartment of Surgery McGovern School of Medicine, University of Texas Health Science Center, Houston, Texas, USA.
Joseph F RappoldDepartment of Surgery Maine Medical Center, Tufts University School of Medicine, Portland, Maine, USA.
Renee SpiegelDepartment of Surgery, Elmhurst Hospital Center, Elmhurst, New York, USA.
Martin A SchreiberDepartment of Surgery, Oregon Health and Sciences University, Portland, Oregon, USA.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Enhancing Resident Investigation and Career Advancement in Cardiovascular and Pulmonary ScienceR38HL143581 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN, HUANG, ALISON · 2018 to 2021
$1.4M
NCATS NIH HHS UL1 TR001872NHLBI NIH HHS R38 HL143581
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood Component TransfusionResuscitationAgedBlood CoagulationCOVID-19COVID-19 SerotherapyEndotheliumFemaleHumansImmunization, PassiveMaleMiddle AgedSARS-CoV-2Wounds and Injuriesacute respiratory distress syndromeCOVID convalescent plasmaCOVID-19endotheliopathy of COVID-19plasmaSARS-CoV-2

Identifiers

PMID34269437
PMCPMC8446992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.