Evidence map›Paper›PMID 34269184›Full record

ReviewNeural regeneration research2022

Transcranial magnetic stimulation in animal models of neurodegeneration.

Mohammad Uzair, Turki Abualait, Muhammad Arshad, Woo-Kyoung Yoo, Ali Mir, Reem Fahd Bunyan, Shahid Bashir

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neural regeneration research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Mohammad UzairDepartment of Biological Sciences, Faculty of Basic & Applied Sciences, International Islamic University Islamabad, Pakistan.
Turki AbualaitCollege of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Muhammad ArshadDepartment of Biological Sciences, Faculty of Basic & Applied Sciences, International Islamic University Islamabad, Pakistan.
Woo-Kyoung YooDepartment of Physical Medicine and Rehabilitation; Hallym Institute for Translational Genomics & Bioinformatics, Hallym University College of Medicine, Anyang, South Korea.
Ali MirNeuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.
Reem Fahd BunyanNeuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.
Shahid BashirNeuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.
King Fahad Specialist Hospital · SAInternational Islamic University, Islamabad · PKHallym University · KRImam Abdulrahman Bin Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain stimulation techniques offer powerful means of modulating the physiology of specific neural structures. In recent years, non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation, have emerged as therapeutic tools for neurology and neuroscience. However, the possible repercussions of these techniques remain unclear, and there are few reports on the incisive recovery mechanisms through brain stimulation. Although several studies have recommended the use of non-invasive brain stimulation in clinical neuroscience, with a special emphasis on TMS, the suggested mechanisms of action have not been confirmed directly at the neural level. Insights into the neural mechanisms of non-invasive brain stimulation would unveil the strategies necessary to enhance the safety and efficacy of this progressive approach. Therefore, animal studies investigating the mechanisms of TMS-induced recovery at the neural level are crucial for the elaboration of non-invasive brain stimulation. Translational research done using animal models has several advantages and is able to investigate knowledge gaps by directly targeting neuronal levels. In this review, we have discussed the role of TMS in different animal models, the impact of animal studies on various disease states, and the findings regarding brain function of animal models after TMS in pharmacology research.

Indexed as

Alzheimer’s diseasedepressionglial cellsneurorehabilitationParkinson’s diseaserepetitive transcranial magnetic stimulationtranscranial direct current stimulationtranscranial magnetic stimulation

Identifiers

PMID34269184
PMCPMC8464007
OpenAlexW3181045513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.