ArticleTransplant international : official journal of the European Society for Organ Transplantation2021
Clinical implementation of coronary computed tomography angiography for routine detection of cardiac allograft vasculopathy in heart transplant patients.
Article in Transplant international : official journal of the European Society for Organ Transplantation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Non-invasive imaging in heart transplant recipients: state of art and future direction.European journal of nuclear medicine and molecular imaging · 2026Review
- Temporal changes in coronary artery calcium in heart transplantation patients.European radiology · 2026Article
- Comparison of image quality between photon-counting detector CT and energy-integrating detector coronary CT angiography in heart transplant patients.The international journal of cardiovascular imaging · 2026Article
- Coronary Computed Tomography Angiography in Heart Transplant Patients: Current Insights and Future Directions.Transplantation · 2025Review
- Temporal changes in CT-derived fractional flow reserve in patients after heart transplantation.European radiology · 2025Article
- Quantitative flow ratio computed from invasive coronary angiography as a predictor for cardiac allograft vasculopathy after cardiac transplant.The international journal of cardiovascular imaging · 2024Article
- Multimodality Imaging in Advanced Heart Failure for Diagnosis, Management and Follow-Up: A Comprehensive Review.Journal of clinical medicine · 2023Review
- New Non-Invasive Imaging Technologies in Cardiac Transplant Follow-Up: Acquired Evidence and Future Options.Diagnostics (Basel, Switzerland) · 2023Review
- Coronary allograft vasculopathy in post-heart transplant patients: pathogenesis and role of cardiac computed tomography in diagnosis-a comprehensive review.Annals of medicine and surgery (2012) · 2023Article
- Epicardial fat volume is related to the degree of cardiac allograft vasculopathy.European radiology · 2023Article
- Cardiac allograft vasculopathy and donor age affecting permanent pacemaker implantation after heart transplantation.ESC heart failure · 2022Article
- Clinicopathological correlations in heart transplantation recipients complicated by death or re-transplantation.Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiac allograft vasculopathy (CAV) is an accelerated form of coronary artery disease that affects long-term outcomes in heart transplant (HTx) patients. We prospectively evaluated the feasibility of coronary computed tomography angiography (CCTA) for the detection of CAV during clinical implementation at our center. All consecutive HTx patients >4 years post-transplant were actively converted from myocardial perfusion imaging to CCTA for the annual assessment of CAV. Between February 2018 and May 2019, 129/172 (75%) HTx patients underwent a CCTA. Renal impairment (n = 21/43) was the most frequent reason for patients could not undergo CCTA. CCTA image quality was good-excellent in 118/129 (92%) patients, and the radiation dose was 2.1 (1.6-2.8) mSv. CCTA showed obstructive CAV in 19/129 (15%) patients. Thirteen (10%) patients underwent additional tests, of which 8 patients underwent coronary revascularization within 90 days of CCTA. After 1 year, 3 additional coronary angiograms were performed, resulting in one revascularization in a patient with known severe CAV who developed ventricular tachycardia. One myocardial infarction after coronary stenting and 2 non-cardiac deaths were observed. CCTA can be successfully implemented for routine detection of CAV with good image quality and low radiation dose. CCTA allows CAV evaluation with the limited need for additional invasive testing.
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