Evidence map›Paper›PMID 34268599›Full record

ArticlePediatric radiology2021

Comparison of ultrafast wave-controlled aliasing in parallel imaging (CAIPI) magnetization-prepared rapid acquisition gradient echo (MP-RAGE) and standard MP-RAGE in non-sedated children: initial clinical experience.

Azadeh Tabari, John Conklin, Maria Gabriela Figueiro Longo, Camilo Jaimes, Kawin Setsompop, Stephen F Cauley, John E Kirsch, Susie Yi Huang, Otto Rapalino, Michael S Gee and 1 more

Abstract read
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Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Azadeh TabariDivision of Pediatric Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA. atabari@partners.org.ORCID http://orcid.org/0000-0002-5685-6401
John ConklinHarvard Medical School, Boston, MA, USA.
Maria Gabriela Figueiro LongoDivision of Pediatric Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
Camilo JaimesHarvard Medical School, Boston, MA, USA.
Kawin SetsompopDivision of Pediatric Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
Stephen F CauleyHarvard Medical School, Boston, MA, USA.
John E KirschHarvard Medical School, Boston, MA, USA.
Susie Yi HuangDivision of Pediatric Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
Otto RapalinoHarvard Medical School, Boston, MA, USA.
Michael S GeeDivision of Pediatric Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
Paul J CarusoDivision of Pediatric Imaging, Department of Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
Harvard University · USMassachusetts General Hospital · USBoston Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFast magnetic resonance imaging (MRI) sequences are advantageous in pediatric imaging as they can lessen child discomfort, decrease motion artifact and improve scanner availability.

objectiveTo evaluate the feasibility of an ultrafast wave-CAIPI (controlled aliasing in parallel imaging) MP-RAGE (magnetization-prepared rapid gradient echo) sequence for brain imaging of awake pediatric patients. MATERIALS AND

methodsEach MRI included a standard MP-RAGE sequence and an ultrafast wave-MP-RAGE sequence. Two neuroradiologists evaluated both sequences in terms of artifacts, noise, anatomical contrast and pathological contrast. A predefined 5-point scale was used by two independent pediatric neuroradiologists. A Wilcoxon signed-rank test was used to evaluate the difference between sequences for each variable.

resultsTwenty-four patients (14 males; mean age: 11.5±4.5 years, range: 1 month to 17.8 years) were included. Wave-CAIPI MP-RAGE provided a 77% reduction in scan time using a 32-channel coil and a 70% reduction using a 20-channel coil. Visualization of the pathology, artifacts and pathological enhancement (including parenchymal, leptomeningeal and dural enhancement) was not significantly different between standard MP-RAGE and wave-CAIPI MP-RAGE (all P>0.05). For central (P<0.001) and peripheral (P<0.001) noise, and the evaluation of the anatomical structures (P<0.001), the observers favored standard MP-RAGE over wave-CAIPI MP-RAGE.

conclusionUltrafast brain imaging with wave-CAIPI MP-RAGE is feasible in awake pediatric patients, providing a substantial reduction in scan time at a cost of subjectively increased image noise.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingAdolescentArtifactsBrainChildHumansMaleAcquisition timeBrainChildrenControlled aliasing in parallel imagingMagnetic resonance imagingParallel imaging

Identifiers

PMID34268599
OpenAlexW3180078863

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.