Evidence map›Paper›PMID 34268480›Full record

ArticleExperimental results2020

Probe the relationship between

Shangru Lyu, Atbin Doroodchi, Yi Sheng, Mark P DeAndrade, Youfeng Yang, Yuning Liu, Michael A Miller, Rui Xiao, Yuqing Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental results, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shangru LyuNorman Fixel Institute for Neurological Diseases, Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Atbin DoroodchiDepartment of Cell Developmental and Integrative Biology, the University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Yi ShengDepartment of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Mark P DeAndradeNorman Fixel Institute for Neurological Diseases, Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Youfeng YangDepartment of Cell Developmental and Integrative Biology, the University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Yuning LiuNorman Fixel Institute for Neurological Diseases, Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Michael A MillerDepartment of Cell Developmental and Integrative Biology, the University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Rui XiaoDepartment of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Yuqing LiNorman Fixel Institute for Neurological Diseases, Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
University of Florida · USUniversity of Alabama at Birmingham · US

Funding

Alabama Neuroscience Blueprint Core CenterP30NS057098 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROTH, KEVIN A · 2006 to 2010
$9.5M
Torsin Function in DrosiphilaP01NS037409 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI OZELIUS, LAURIE J. · 1999 to 2007
$8.5M
UAB Neuroscience Core CenterP30NS047466 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BRITT, WILLIAM JARVIS · 2005 to 2019
$8.5M
Dissecting the mechanisms of Alzheimer's disease (AD)-related smell loss in a C. elegans AD modelR01AG063766 · NIA · UNIVERSITY OF FLORIDA · PI XIAO, RUI · 2019 to 2023
$1.9M
Restless Legs Syndrome: Pathophysiology using Btbd9 Conditional Knockout MiceR01NS082244 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING · 2014 to 2018
$1.6M
Pathophysiology of DYT1 Dystonia: Targeted Mouse ModelsR01NS054246 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING · 2007 to 2010
$1.4M
Pathophysiology and Animal Model of Restless Legs Syndrome (RLS): Btbd9 Null MicR21NS065273 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING · 2009 to 2010
$401k
Rapid-onset Dystonia Parkinsonism (DYT12 Dystonia): Pathophysiology & Atp1a3 MiceR21NS072872 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING · 2010 to 2011
$399k
Pathophysiology of Myoclonas-Dystonia: Sgce Mutant MiceR21NS047692 · NINDS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI LI, YUQING · 2005 to 2006
$383k
Characterization of epsilon-sarcoglycan interacting proteins in mouse brainR03NS074423 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING · 2011 to 2012
$147k
NIA NIH HHS R01 AG063766NINDS NIH HHS P01 NS037409NINDS NIH HHS P30 NS047466NINDS NIH HHS P30 NS057098NINDS NIH HHS R01 NS054246NINDS NIH HHS R01 NS082244NINDS NIH HHS R03 NS074423NINDS NIH HHS R21 NS047692NINDS NIH HHS R21 NS065273NINDS NIH HHS R21 NS072872
6 · The paper itself

Abstract

Restless legs syndrome (RLS) is a neurological disorder characterized by an urge to move and uncomfortable sensations. Genetic studies have identified polymorphisms in up to 19 risk loci, including

Indexed as

Btbd9hpo-9Meis1restless legs syndromeunc-62

Identifiers

PMID34268480
PMCPMC8279044
OpenAlexW3014917781

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.