ReviewAlzheimer's & dementia (New York, N. Y.)2021
A systematic review and network meta-analysis of interventions for subjective cognitive decline.
Review in Alzheimer's & dementia (New York, N. Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06632145 (Cog-Fun Ageing Participation-centered, Health Promotion for Older Adult), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cog-Fun Ageing Participation-centered, Health Promotion for Older Adult
Who cites it
23 citing papers in PubMed.
- Effects of multisession frontoparietal network anodal tDCS and cognitive rehabilitation on subjective cognitive impairment: a double-blind RCT.BMC neurology · 2026Trial
- Targeting brain health in subjective cognitive decline: insights from a multidomain randomized controlled trial.Aging clinical and experimental research · 2025Trial
- Effectiveness of a Meta-Cognitive Group Intervention for Older Adults with Subjective Cognitive Decline or Mild Cognitive Impairment: The ASPIRE Randomized Controlled Trial.The journal of prevention of Alzheimer's disease · 2024Trial
- Efficacy of a Mobile-Based Multidomain Intervention to Improve Cognitive Function and Health-Related Outcomes Among Older Korean Adults with Subjective Cognitive Decline.Journal of Alzheimer's disease : JAD · 2023Trial
- User-Centered Design and Evaluation of a "Lehuo Pingpang" Exergame for Older Adults With Mild Cognitive Impairment: Cross-Sectional Convergent Mixed Methods Study.JMIR serious games · 2026Article
- Subjective cognitive decline and impacts among US cancer survivors: Associations with cancer characteristics and social determinants of health.Journal of cancer survivorship : research and practice · 2026Article
- Feasibility, Usability and Acceptance of a Multi-Component Cognitive Intervention Using Immersive Virtual Reality and Telemedicine in Individuals with Subjective Cognitive Decline.Journal of clinical medicine · 2026Article
- Article
- Memory training through Chinese classics recitation for individuals with subjective cognitive decline: study protocol for a pilot study.Frontiers in aging neuroscience · 2026Article
- Early Detection of Cognitive Decline: Executive Functioning Index R4Alz-pc Predicts Memory-Related Concerns in Community Adults.Diagnostics (Basel, Switzerland) · 2025Article
- The Experience of and Needs for Exergames in Older Adults With Mild Cognitive Impairment: Qualitative Interview Study.JMIR serious games · 2025Article
- Towards characterizing subjective cognitive decline in older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Distinct trajectories of subjective cognitive decline before diagnosis of neurocognitive disorders: Longitudinal modelling over 18 years.The journal of prevention of Alzheimer's disease · 2025Article
- Subjective Memory Complaints: A Conceptual Analysis.Journal of multidisciplinary healthcare · 2025Review
- Exploring neurofeedback as a therapeutic intervention for subjective cognitive decline.The European journal of neuroscience · 2024Article
- Effects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis.BMC medicine · 2024Article
- Subjective Cognitive Decline in Community-Dwelling Older Adults With Objectively Normal Cognition: Mediation by Depression and Instrumental Activities of Daily Living.Psychiatry investigation · 2024Article
- Subjective cognitive decline in Brazil: Prevalence and association with dementia modifiable risk factors in a population-based study.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- MASCoD-Multidimensional Assessment of Subjective Cognitive Decline.Frontiers in psychology · 2022Article
- A systematic review and network meta-analysis of interventions for subjective cognitive decline.Alzheimer's & dementia (New York, N. Y.) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubjective cognitive decline (SCD) is considered a risk factor for Alzheimer's disease (AD), highlighting the need for identifying and ranking effective interventions. This was addressed in a systematic review and network meta-analysis (NMA) of pharmacological and non-pharmacological interventions for SCD.
methodsMEDLINE, Web of Science Core Collection, CENTRAL, and PsycINFO were searched for randomized controlled trials (RCTs) investigating effects on memory, global cognition, and quality of life. Random-effect model NMAs were conducted. The Cochrane Risk-of-Bias-2 tool assessed methodological quality. Prospero-Registration: CRD42020180457.
resultsThe systematic review included 56 RCTs. Education programs were most effective for improving memory, second most effective for improving global cognition. Quality of life and adverse events could not be included due to insufficient data. Overall methodological quality of studies was low.
conclusionEducation programs were most effective for improving memory and cognition, warranting further research into effective elements of this intervention. There is urgent need to address identified methodological shortcomings in SCD intervention research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.