Evidence map›Paper›PMID 34268389›Full record

ArticleAnnals of translational medicine2021

Do the positioning variables of the cage contribute to adjacent facet joint degeneration? Radiological and clinical analysis following intervertebral fusion.

Fuping Li, Xinhua Zhan, Xin Xi, Zhili Zeng, Bin Ma, Ning Xie, Rui Zhu, Tsung-Yuan Tsai, Guoan Li, Yan Yu and 1 more

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Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Advances and Prospects in Biomaterials for Intervertebral Disk Regeneration.Frontiers in bioengineering and biotechnology · 2021
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fuping LiDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Xinhua ZhanJiading Branch of Shanghai General Hospital, Shanghai, China.
Xin XiDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Zhili ZengDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Bin MaDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Ning XieDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Rui ZhuKey Laboratory of Spine and Spinal Cord Injury Repair and Regeneration, Ministry of Education, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Tsung-Yuan TsaiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Guoan LiOrthopedic Bioengineering Research Center, Department of Orthopedic Surgery, Newton-Wellesley, Hospital/Harvard Medical School, Wellesley, MA, USA.
Yan YuDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Liming ChengDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCompared to other risk factors, adjacent facet joint degeneration (AFD) is the main contributor to adjacent segment disease (ASD). The interbody cage may be a potential indirect risk of AFD. This study investigated the correlations among the lumbar sagittal balance parameters, the inter-body cage's intraoperative positioning variables, and adjacent facet joint degeneration following the transforaminal lumbar interbody fusion (TLIF) technique.

methodsPatients who accepted single-level TLIF for symptomatic lumbar degenerative disease and were followed up for at least six months were enrolled in this study. According to the inclusive and exclusive criteria, 93 patients were included (44 males and 49 females). X-ray and computed tomography (CT) images were obtained before and six months after surgery. The vertebral contour and the center of the marker mass in the cage were calculated using a geometric algorithm. Orthopedic surgeons measured the disc height, lordosis angle, and facet joint degeneration. Patient-reported outcomes, including the Oswestry Disability Index (ODI) and the visual analog scale (VAS), were used to assess the clinical outcomes. The Student's t-test, Wilcoxon rank-sum test, and Chi-square test were used for the statistical analyses.

resultsThe average age was 53.7 years old (range, 27-84 years). The average functional disability outcome assessed by the ODI was 61.2, and the average back and leg pain assessed by the VAS was 6.2 and 6.9, respectively. The patients were categorized into a normal group and an abnormal (AFD) group according to whether the facet joint degeneration was aggravated. The abnormal group had a higher back pain VAS score (P=0.031) and lower sagittal vertical position (P=0.027). The other parameters were similar at baseline (P>0.05). The cage's sagittal vertical position decreased significantly with AFD aggravation (OR, 0.737; 95% CI, 0.561-0.969).

conclusionsIn patients with AFD aggravation, the preoperative VAS and postoperative ODI scores were significantly higher. The cage position parameters were related to AFD. A lower cage center was associated with a greater incidence of AFD.

Indexed as

adjacent facet joint degeneration (AFD)Adjacent segment disease (ASD)interbody cagetransforaminal lumbar interbody fusion

Identifiers

PMID34268389
PMCPMC8246202

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