ArticleAnnals of translational medicine2021
The role of the vaginal microbiome in distinguishing female chronic pelvic pain caused by endometriosis/adenomyosis.
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The Microbiome Landscape of Adenomyosis: A Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2025Pooled it
- Correlation between dysbiosis of vaginal microecology and endometriosis: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Microbiome and chronic pelvic pain in women: a mini-review.Human reproduction (Oxford, England) · 2026Review
- Assessing the female urogenital-rectal axis microbiome: focus on endometriosis and recurrent implantation failure.Reproductive biology and endocrinology : RB&E · 2026Article
- Decoding the microbial landscape of endometrial cancer: a case-control study.BMC microbiology · 2026Article
- Bacterial microbiome analysis of vaginal, cervical, and endometrial samples in patients with adenomyosis during the window of implantation.Microbiology spectrum · 2026Article
- Intestinal microbiota alteration in women with adenomyosis and clinical characteristics correlation.Frontiers in microbiology · 2026Article
- Microbiota insights in endometriosis.Microbiome · 2025Review
- Article
- Oral, Vaginal, and Stool Microbial Signatures in Patients With Endometriosis as Potential Diagnostic Non-Invasive Biomarkers: A Prospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Clinical efficacy of etonogestrel implants on relieving dysmenorrhea in endometriosis and adenomyosis women for up to 3 years.Frontiers in medicine · 2025Article
- Reproductive tract microbiome dysbiosis associated with gynecological diseases.Frontiers in cellular and infection microbiology · 2025Review
- Microbiome dysbiosis and endometriosis: a systematic scoping review of current literature and knowledge gaps.Human reproduction open · 2025Review
- Endometriosis specific vaginal microbiota links to urine and serum N-glycome.Scientific reports · 2024Article
- Vaginal and rectal microbiome contribute to genital inflammation in chronic pelvic pain.BMC medicine · 2024Article
- Comparative analysis of endometrial, vaginal, and gut microbiota in patients with and without adenomyosis.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Comparison of cervicovaginal fluid extracellular vesicles isolated from paired cervical brushes and vaginal swabs.Journal of extracellular biology · 2024Article
- Diagnostic and therapeutic approaches for endometriosis: a patent landscape.Archives of gynecology and obstetrics · 2024Review
- Snowflake: visualizing microbiome abundance tables as multivariate bipartite graphs.Frontiers in bioinformatics · 2024Article
- Current Updates on the Role of Microbiome in Endometriosis: A Narrative Review.Microorganisms · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to investigate the specific vaginal microbiome in the differential diagnosis of endometriosis/adenomyosis (EM/AM)-associated chronic pelvic pain (CPP) from other types of CPP, and to explore the role of the vaginal microbiome in the mechanism of EM/AM-associated CPP.
methodsWe recruited 37 women with EM/AM-associated CPP, 25 women with chronic pelvic pain syndrome (CPPS) without EM/AM, and 66 women without CPPS into our study. All of the participants were free from human papillomavirus (HPV) infection. Sequencing of barcoded 16S rRNA gene fragments (V4) was used to determine the vaginal microbiome composition on the Illumina HiSeq2500 System. Taxonomic and functional bioinformatics analyses were performed using
resultsAt the species level, EM/AM-associated CPP was found to be associated with a predominance of
conclusionsCompared to that of CPPS patients without EM/AM and women without CPPS, the vaginal microbiome of patients with EM/AM-associated CPP shows significantly higher alpha (phylogenetic) diversity, as well as higher counts of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.