Evidence map›Paper›PMID 34268352›Full record

ArticleAnnals of translational medicine2021

Association of serum monomeric periostin level with outcomes of acute exacerbation of idiopathic pulmonary fibrosis and fibrosing nonspecific interstitial pneumonia.

Hiroshige Shimizu, Susumu Sakamoto, Masaki Okamoto, Takuma Isshiki, Junya Ono, Shigeki Shimizu, Tomoaki Hoshino, Kenji Izuhara, Sakae Homma

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Acute Exacerbations of Interstitial Lung Diseases: Focus on Biomarkers.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Hiroshige ShimizuDepartment of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, Japan.
Susumu SakamotoDepartment of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, Japan.
Masaki OkamotoDivision of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan.
Takuma IsshikiDepartment of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, Japan.
Junya OnoShino-Test Corporation, Sagamihara, Japan.
Shigeki ShimizuDepartment of Pathology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Tomoaki HoshinoDivision of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan.
Kenji IzuharaDivision of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan.
Sakae HommaDepartment of Respiratory Medicine, Toho University Omori Medical Center, Tokyo, Japan.
Toho University Omori Medical Center · JPKurume University · JPKindai University · JPSaga Medical School Hospital · JPShino-Test CorporationToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe associations of serum monomeric periostin (M-PN) level and serial change in M-PN with acute exacerbation of chronic fibrosing interstitial pneumonia (AE-FIP) are unclear.

methodsWe prospectively measured serum M-PN level from onset of AE to day 14 in 37 patients with AE-FIP and evaluated its association with outcome. To determine localization of periostin expression, immunohistochemical staining of pathological lung tissue from autopsy cases of AE-IPF was evaluated.

resultsData from 37 AE-FIP patients (28 men; age 73.9±7.8 years) were analyzed. With healthy controls as reference, serum M-PN level was significantly higher in patients with AE-FIP (P=0.02) but not in those with stable idiopathic pulmonary fibrosis (P=1.00). M-PN was significantly lower on day 7 than at AE-FIP onset in survivors [14.6±5.8

conclusionsSerial change in serum M-PN level may be a prognostic indicator of AE-FIP.

Indexed as

Acute exacerbationfibrosing interstitial pneumoniamonomeric periostin

Identifiers

PMID34268352
PMCPMC8246219
OpenAlexW3157520635

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.