ReviewFrontiers in nutrition2021
Polyphenol-Mediated Gut Microbiota Modulation: Toward Prebiotics and Further.
Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 236 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
236 citing papers in PubMed, 4 syntheses or guidelines pooled it, 407 citations in OpenAlex.
- The Integrative Role of Berberine in Gut Microbiota Modulation and Cardiometabolic Outcomes: A Systematic Review of Randomised Clinical Trials.Nutrients · 2026Pooled it
- Dietary Polyphenols as Modulators ofNutrients · 2026Pooled it
- Pooled it
- A systematic review: polyphenol's effect on food allergy via microbiome modulation.Frontiers in microbiology · 2025Pooled it
- Trial
- Trial
- Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people.Microbiology spectrum · 2025Trial
- Trial
- Trial
- Dark Chocolate Intake Positively Modulates Gut Permeability in Elite Football Athletes: A Randomized Controlled Study.Nutrients · 2023Trial
- Establishment of a Diet-Induced Systemic Metabolic SyndromeModel Reveals Early Renal Alterations and the Nephroprotective Potential of Three Jabuticaba (Myrciaria cauliflora) Formulations.Journal of molecular histology · 2026Article
- Article
- Beneficial Effects of Nuts on Cardiovascular and Metabolic Health: An Insight into the Gut-Cardiometabolic Axis.Current developments in nutrition · 2026Review
- Anti-Browning and Prebiotic Effects of White Tea Extract on Fresh-Cut Lotus Root.Food science & nutrition · 2026Article
- Elucidating the Multifunctional Roles of Olive Oil By-Products: Phenolic Profiles, Antioxidant Capacity, Probiotic Growth-Promoting and Antimicrobial Activity.Foods (Basel, Switzerland) · 2026Article
- Cranberry Extract and Polyphenol Metabolites Modulate Luminal and Mucosal Microbiome.International journal of molecular sciences · 2026Article
- Alginate-Grape Pomace Flour Microcapsules for Enhanced Protection and Delivery of Lacticaseibacillus rhamnosus GG.Probiotics and antimicrobial proteins · 2026Article
- In vitro selective inhibitory activity of ethnoveterinary plant extracts, antibiotic growth promoters, antibiotics, phytochemicals and their synthetic analogues against diarrhoea-associated and probiotic-bacteria of livestock.Veterinary research communications · 2026Article
- Dietary Matcha Attenuates High-Fat High-Sugar Diet-Induced Cardiomyocyte Hypertrophy in Association with Gut Microbiota Remodeling in Mice.Nutrients · 2026Article
- Microbiome and chronic pelvic pain in women: a mini-review.Human reproduction (Oxford, England) · 2026Review
176 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genome of gut microbes encodes a collection of enzymes whose metabolic functions contribute to the bioavailability and bioactivity of unabsorbed (poly)phenols. Datasets from high throughput sequencing, metabolome measurements, and other omics have expanded the understanding of the different modes of actions by which (poly)phenols modulate the microbiome conferring health benefits to the host. Progress have been made to identify direct prebiotic effects of (poly)phenols; albeit up to date, these compounds are not recognized as prebiotics
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.