Evidence map›Paper›PMID 34268301›Full record

ArticleFrontiers in cell and developmental biology2021

Using Zebrafish to Elucidate Glial-Vascular Interactions During CNS Development.

Robyn A Umans, Carolyn Pollock, William A Mills, Kareem C Clark, Y Albert Pan, Harald Sontheimer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. GlialeLife · 2026
    Article
  2. Article
  3. Article
  4. Homemade: building the structure of the neurogenic niche.Frontiers in cell and developmental biology · 2023
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robyn A UmansGlial Biology in Health, Disease, and Cancer Center, The Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States.
Carolyn PollockSchool of Neuroscience, Virginia Tech, Blacksburg, VA, United States.
William A MillsGlial Biology in Health, Disease, and Cancer Center, The Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States.
Kareem C ClarkCenter for Neurobiology Research, The Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States.
Y Albert PanCenter for Neurobiology Research, The Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States.
Harald SontheimerGlial Biology in Health, Disease, and Cancer Center, The Fralin Biomedical Research Institute at VTC, Roanoke, VA, United States.
Biomedical Research Institute · USVirginia Tech · US

Funding

Amino Acid Transport and the Biology of Human GliomasR01NS052634 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SONTHEIMER, HARALD W · 2005 to 2015
$3.7M
Regulation of Amino-acid Transport in Human GliomasR01CA227149 · NCI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SONTHEIMER, HARALD W · 2019 to 2023
$1.8M
Glioma-Astrocyte Vascular InteractionsR01NS082851 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SONTHEIMER, HARALD W · 2013 to 2016
$1.3M
NCI NIH HHS R01 CA227149NINDS NIH HHS R01 NS052634NINDS NIH HHS R01 NS082851
6 · The paper itself

Abstract

An emerging area of interest in Neuroscience is the cellular relationship between glia and blood vessels, as many of the presumptive support roles of glia require an association with the vasculature. These interactions are best studied

Indexed as

angiogenesisbrain developmentgliavasculaturezebrafish

Identifiers

PMID34268301
PMCPMC8276133
OpenAlexW3177050894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.