ReviewGland surgery2021
Pattern of local recurrence after mastectomy and reconstruction in breast cancer patients: a systematic review.
Review in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Detection of residual fibroglandular tissue on breast MRI and associated factors in women treated with mastectomy and DIEP flap breast reconstruction.Insights into imaging · 2026Article
- Breast Cancer Local Recurrence in Patients With and Without Post-Mastectomy Immediate Breast Reconstruction: Systematic Review and Meta-Analysis.Plastic surgery (Oakville, Ont.) · 2026Review
- The comparison outcome of implant-based breast reconstruction with acellular dermal matrix, non-acellular dermal matrix and TiLOOPGland surgery · 2026Article
- Oncologic outcomes after poly-4-hydroxybutyrate scaffold in post-mastectomy breast reconstruction: a retrospective, multi-center cohort study.World journal of surgical oncology · 2026Article
- Outcomes and recurrence trends after skin-sparing mastectomy and immediate DIEP flap reconstruction: A single-centre analysis.JPRAS open · 2026Article
- Clinically Silent Local Recurrence of Breast Cancer Detected in a Mastectomy Scar During DIEP Flap Reconstruction: A Case Report.Clinical case reports · 2026Article
- The inframammary fold: Structure, clinical considerations, and reconstructive techniques.JPRAS open · 2026Review
- Early Local Recurrence as Invasive Micropapillary Carcinoma after Skin-Sparing Mastectomy with Immediate Deep Inferior Epigastric Perforator Flap Reconstruction for Ductal CarcinomaSurgical case reports · 2026Article
- Article
- Modified Keystone a Versatile Flap Reconstruction for Mastectomy Defects: Our Clinical Experience.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2025Article
- Comparison of locoregional recurrence risk among nipple-sparing mastectomy, skin-sparing mastectomy, and simple mastectomy in patients with ductal carcinoma in situ: a single-center study.Breast cancer (Tokyo, Japan) · 2024Article
- Molecular subtype and risk of local recurrence after nipple‑sparing mastectomy for breast cancer.Oncology letters · 2024Article
- Histologic Examination of Mastectomy Scars during Breast Reconstruction: A Systematic Review.Plastic and reconstructive surgery. Global open · 2024Article
- Postoperative Outcomes of Pre-Pectoral Versus Sub-Pectoral Implant Immediate Breast Reconstruction.Cancers · 2024Article
- Long-Term Outcomes of Breast Cancer Patients with Local Recurrence After Mastectomy Undergoing Immediate Breast Reconstruction: A Retrospective Multi-institutional Study of 4153 Cases.Annals of surgical oncology · 2023Article
- Parasitization of the pedicle: a rare form of TRAM flap recurrence.Journal of surgical case reports · 2023Article
- Oncoplastic and reconstructive breast surgery.Frontiers in oncology · 2023Review
- Breast cancer local recurrence after mastectomy with immediate latissimus dorsi myocutaneous flap reconstruction: A case report.SAGE open medical case reports · 2023Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to describe the locations of local recurrences based on the mastectomy and reconstruction type in breast cancer patients.
methodsIn November 2020, a systematic literature review was performed through MEDLINE/PubMed and the Cochrane Centre Register of Controlled Trials. Publications that included skin-sparing or nipple-sparing mastectomy followed by breast reconstruction and described the location of local recurrences were analyzed. Exclusion criteria included salvage or prophylactic mastectomy, unclear distinction between local and regional recurrences, rare tumor types.
resultsFrom 19 publications, 272 local recurrences lesions were reported in a total of 4,787 patients. After autologous reconstruction (n=2,465), local recurrences were located in the skin in 45 (1.8%) patients, in the chest wall in 18 (0.7%), and in the nipple-areolar complex in 9 (0.4%). After implant reconstruction (n=1,917), local recurrences sites included the skin in 91 (4.7%) patients, chest wall in 8 (0.4%), and nipple-areolar complex in 8 (0.4%). Of the 70 lesions with reported in-breast location, 57 (81.4%) relapsed in the original tumor location. DISCUSSION: Although meta-analysis was not conducted, present analysis demonstrated that most local recurrences after skin-sparing or nipple-sparing mastectomy occurred within the skin or subcutaneous tissues. It was found that the original tumor location was the most frequent site of relapse. Therefore, special attention should be paid to the original tumor overlying the skin while planning postmastectomy radiation therapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.