Evidence map›Paper›PMID 34268070›Full record

ArticleGland surgery2021

Pancreatoduodenectomy within 2 weeks after endoscopic retrograde cholangio-pancreatography increases the risk of organ/space surgical site infections: a 5-year retrospective cohort study in a high-volume centre.

Wensen Chen, Kai Zhang, Zhongheng Zhang, Zipeng Lu, Daoquan Zhang, Juan Liu, Yue Yang, Yinzhi Leng, Yongxiang Zhang, Weihong Zhang and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Impact of Extended Antibiotic Use After Pancreaticoduodenectomy for Patients with Preoperative Metallic Biliary Stenting Treated with Neoadjuvant Chemotherapy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Wensen ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Kai ZhangPancreas Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhongheng ZhangDepartment of Emergency Medicine, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zipeng LuPancreas Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Daoquan ZhangDepartment of Endoscopy, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Juan LiuOffice of Infection Management, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yue YangOffice of Infection Management, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yinzhi LengDepartment of Infection, Nanjing Traditional Chinese Medicine Hospital, Nanjing, China.
Yongxiang ZhangOffice of Infection Management, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Weihong ZhangOffice of Infection Management, Jiangsu Province Hospital & Jiangsu Shengze Hospital, Suzhou, China.
Kuirong JiangPancreas Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Guihua ZhuangDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yi MiaoPancreas Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yun LiuDepartment of Geriatrics Endocrinology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNXi'an Jiaotong University · CNJiangsu Shengze Hospital · CNNanjing Traditional Chinese Medicine Hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrgan/space surgical site infections (OSSI) after pancreaticoduodenectomy (PD) are not rare events. The role of diagnosis and treatment for pancreatic and biliary diseases with an endoscopic retrograde cholangio-pancreatography (ERCP) procedure is currently controversial. However, the ERCP procedure might play a role in surgical outcomes after PD.

methodsWe conducted a retrospective cohort study for patients who underwent PD in the First Affiliated Hospital with the Nanjing Medical University from 1st September 2012 to 31st January 2018. The relationship between ERCP exposure and OSSI after PD was analyzed by univariate and forward stepwise multivariate logistic regression model.

resultsOf the 1,365 patients who underwent PD, 136 developed OSSI (10.0%). We found that ERCP exposure before PD (EEBPD) was significantly associated with an increased incidence rate of post-operative pancreas fistula (POPF) [24.2% (23/95)

conclusionsERCP, as an independent risk factor, significantly increased the risk of post-operative OSSI after PD if it is performed within 14 days prior to surgery. Our findings would assist clinical decision-making, and improve OSSI control and prevention.

Indexed as

Endoscopic retrograde cholangio-pancreatography (ERCP)logistic regressionorgan/space surgical site infections (OSSI)pancreaticoduodenectomy (PD)

Identifiers

PMID34268070
PMCPMC8258873
OpenAlexW3166889779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.