Evidence map›Paper›PMID 34268014›Full record

ArticlePeerJ2021

The effects of hip- and ankle-focused exercise intervention on dynamic knee valgus: a systematic review.

Farhah Nadhirah Aiman Sahabuddin, Nazatul Izzati Jamaludin, Nurul Hidayah Amir, Shazlin Shaharudin

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07465380 (Functional Stabilization Training VS Comprehensive Corrective Exercises on Lower Limb Kinematics in Patellofemoral Pain and Dynamic Knee Valgus), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07465380 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Functional Stabilization Training VS Comprehensive Corrective Exercises on Lower Limb Kinematics in Patellofemoral Pain and Dynamic Knee Valgus

TypeinterventionalSponsorAhram Canadian UniversityRan2026 to 2027Enrolled60ConditionsPatellofemoral Pain SyndromeArmsStandard Care Exercise Program (SC), Functional Stabilization Training (FST), Comprehensive Corrective Exercise Program (CCEP)
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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  13. Impact of the Quadriceps Angle on Health and Injury Risk in Female Athletes.International journal of environmental research and public health · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Farhah Nadhirah Aiman SahabuddinExercise and Sports Science Programme, School of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Nazatul Izzati JamaludinExercise and Sports Science Programme, School of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Nurul Hidayah AmirDepartment of Translational Health Sciences, Faculty of Health Science, University of Bristol, Bristol, United Kingdom.
Shazlin ShaharudinExercise and Sports Science Programme, School of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Hospital Universiti Sains Malaysia · MYUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA range of non-contact injuries such as anterior cruciate ligament tear, and patellofemoral pain syndrome are caused by disordered knee joint loading from excessive dynamic knee valgus (DKV). Previous systematic reviews showed that DKV could be modified through the influence of hip strength and ankle range of motion. Therefore, the purpose of this systematic review was to examine the effects of exercise intervention which involved either top-down or bottom-up kinetic chains on minimizing DKV in male and female adults and adolescents, with and without existing knee pain. METHODOLOGY: Electronic searches were conducted in SAGE, Science Direct, SCOPUS, and Pubmed. The search strategy consisted of medical subject headings and free-text search keywords, synonyms and variations of 'exercise intervention,' 'knee alignment,' 'dynamic knee valgus', 'knee abduction' that were merged via the Boolean operator 'AND' and 'OR'. The search was conducted on full-text journals that documented the impact of the exercise intervention program involving either the bottom-up or top-down DKV mechanism on the knee kinematics. Furthermore, exercise intervention in this review should last at least one week which included two or three sessions per week. This review also considered both men and women of all ages with a healthy or symptomatic knee problem. The risk of bias of the included studies was assessed by Cochrane risk assessment tool. The protocol of this review was registered at PROSPERO (registration number: CRD42021219121).

resultsTen studies with a total of 423 participants (male = 22.7%, female = 77.3%; adults = 249, adolescents = 123; pre-adolescent = 51) met the inclusion criteria of this review. Seven studies showed the significant effects of the exercise intervention program (range from two weeks to ten weeks) on reducing DKV. The exercise training in these seven studies focused on muscle groups directly attached to the knee joint such as hamstrings and gastrocnemius. The remaining three studies did not show significant improvement in DKV after the exercise intervention (range between eight weeks to twelve weeks) probably because they focused on trunk and back muscles instead of muscles crossing the knee joint.

conclusionExercises targeting specific knee-joint muscles, either from top-down or bottom-up kinetic chain, are likely to reduce DKV formation. These results may assist athletes and coaches to develop effective exercise program that could minimize DKV and ultimately prevent lower limb injuries.

Indexed as

BiomechanicsHuman healthKinetic chainKnee alignmentStrength training

Identifiers

PMID34268014
PMCPMC8265381
OpenAlexW3178423932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.