Evidence map›Paper›PMID 34267947›Full record

ArticleJournal of clinical and translational science2021

Attitudes toward genomics and precision medicine.

James M DuBois, Jessica Mozersky, Alison Antes, Tammy English, Meredith V Parsons, Kari Baldwin

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical and translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06386861 (Developing Culturally-Tailored Interventions to Overcome Genomic Health Disparities in Communities of Color), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06386861 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Developing Culturally-Tailored Interventions to Overcome Genomic Health Disparities in Communities of Color

TypeinterventionalSponsorBoston CollegeRan2024 to 2025Enrolled851ConditionsAdult ALLArmsAttitudes Toward Genomics and Precision Medicine (English), Attitudes Toward Genomics and Precision Medicine (Spanish)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

James M DuBoisDivision of General Medical Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-3712-7051
Jessica MozerskyDivision of General Medical Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-4942-4571
Alison AntesDivision of General Medical Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-2632-7701
Tammy EnglishDepartment of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Meredith V ParsonsDivision of General Medical Sciences, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0002-8869-3766
Kari BaldwinDivision of General Medical Sciences, Washington University School of Medicine, St. Louis, MO, USA.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
FOSTERING INTEGRITY AND SOCIETAL IMPACT IN GENOMICS THROUGH MANAGEMENT AND LEADERSHIP PRACTICESK01HG008990 · NHGRI · WASHINGTON UNIVERSITY · PI ANTES, ALISON L · 2016 to 2020
$599k
NCATS NIH HHS UL1 TR002345NHGRI NIH HHS K01 HG008990
6 · The paper itself

Abstract

purposeThis paper reports on a novel measure, attitudes toward genomics and precision medicine (AGPM), which evaluates attitudes toward activities such as genetic testing, collecting information on lifestyle, and genome editing - activities necessary to achieve the goals of precision medicine. DISCUSSION: The AGPM will be useful for researchers who want to explore attitudes toward genomics and precision medicine. The association of concerns about precision medicine activities with demographic variables such as religion and politics, as well as higher levels of education, suggests that further education on genomic and precision activities alone is unlikely to shift AGPM scores significantly.

methodsWe wrote items to represent psychological and health benefits of precision medicine activities, and concerns about privacy, social justice, harm to embryos, and interfering with nature. We validated the measure through factor analysis of its structure, and testing associations with trust in the health information system and demographic variables such as age, sex, education, and religion.

resultsThe AGPM had excellent alpha reliability (.92) and demonstrated good convergent validity with existing measures. Variables most strongly associated with higher levels of concern with precision medicine activities included: regular religious practice, republican political leanings, and higher levels of education.

Indexed as

attitudesBioethicsELSImeasurementprecision medicine

Identifiers

PMID34267947
PMCPMC8278159

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.