Evidence map›Paper›PMID 34267897›Full record

ArticleClinical case reports2021

The first reported case of Noonan syndrome complicated with hepatocellular carcinoma.

Satoru Kakizaki, Daisuke Uehara, Hiroki Tojima, Takayoshi Suga, Yuichi Yamazaki, Ken Sato, Norio Kubo, Ken Shirabe, Takayuki Yokota, Kei Shibuya and 4 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Satoru KakizakiDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.ORCID https://orcid.org/0000-0003-0224-7093
Daisuke UeharaDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Hiroki TojimaDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Takayoshi SugaDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Yuichi YamazakiDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Ken SatoDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Norio KuboDepartment of General Surgical Science Gunma University Graduate School of Medicine Maebashi Japan.
Ken ShirabeDepartment of General Surgical Science Gunma University Graduate School of Medicine Maebashi Japan.
Takayuki YokotaDepartment of Diagnostic Radiology and Nuclear Medicine Gunma University Graduate School of Medicine Maebashi Japan.
Kei ShibuyaGunma University Heavy Ion Medical Center Maebashi Japan.
Tatsurou MaeharaDepartment of Human Pathology Gunma University Graduate School of Medicine Maebashi Japan.
Hideaki YokooDepartment of Human Pathology Gunma University Graduate School of Medicine Maebashi Japan.
Atsushi NaganumaDepartment of Gastroenterology National Hospital Organization Takasaki General Medical Center Takasaki Japan.
Toshio UraokaDepartment of Gastroenterology and Hepatology Gunma University Graduate School of Medicine Maebashi Japan.
Gunma University · JPGunma University Hospital · JPNational Hospital Organization Takasaki Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noonan syndrome is a genetic multisystem disorder and is associated with mutation of genes encoding the proteins in the RAS-MAPK pathway. We reported the first case of Noonan syndrome complicated with hepatocellular carcinoma.

Indexed as

hepatocellular carcinomaNoonan syndromePTPN11

Identifiers

PMID34267897
PMCPMC8271263
OpenAlexW3148259061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.