Evidence map›Paper›PMID 34267878›Full record

ArticleACS medicinal chemistry letters2021

A New Highly Deuterated [

Hao Xiao, Seok Rye Choi, Ruiyue Zhao, Karl Ploessl, David Alexoff, Lin Zhu, Zhihao Zha, Hank F Kung

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Development ofMolecular imaging and biology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Metabolic Stability of the Demyelination Positron Emission Tomography Tracer [The Journal of pharmacology and experimental therapeutics · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao XiaoBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing 100069, China.
Seok Rye ChoiFive Eleven Pharma Inc., Philadelphia, Pennsylvania 19104, United States.
Ruiyue ZhaoDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Karl PloesslFive Eleven Pharma Inc., Philadelphia, Pennsylvania 19104, United States.ORCID https://orcid.org/0000-0001-7896-5900
David AlexoffFive Eleven Pharma Inc., Philadelphia, Pennsylvania 19104, United States.
Lin ZhuKey Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID https://orcid.org/0000-0001-9530-8531
Zhihao ZhaFive Eleven Pharma Inc., Philadelphia, Pennsylvania 19104, United States.
Hank F KungFive Eleven Pharma Inc., Philadelphia, Pennsylvania 19104, United States.ORCID https://orcid.org/0000-0003-3254-8049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[

Identifiers

PMID34267878
PMCPMC8274066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.