Evidence map›Paper›PMID 34267829›Full record

ReviewGastroenterology research2021

A Focused Review on Recent Advances in the Diagnosis and Treatment of Viral Hepatitis.

Wei Zhang, Mahmoud Aryan, Steve Qian, Roniel Cabrera, Xiuli Liu

Open access · diamondAbstract readReview
In one paragraph

Review in Gastroenterology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wei ZhangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Florida, Gainesville, FL, USA.
Mahmoud AryanDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Steve QianDepartment of Internal Medicine, University of Florida, Gainesville, FL, USA.
Roniel CabreraDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Florida, Gainesville, FL, USA.
Xiuli LiuDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA.
University of Florida · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global burden of viral hepatitis remains substantial despite advances in antiviral therapy and effective vaccines. There are five hepatitis viruses (hepatitis A, B, C, D, and E). Mortality related to hepatitis B virus and hepatitis C virus infections is among the top four global infectious diseases, together with human immunodeficiency virus infection, malaria, and tuberculosis. Of those deaths, approximately 47% are attributable to hepatitis B virus, 48% to hepatitis C virus and the remainder to hepatitis A virus and hepatitis E virus. Ending hepatitis epidemics as a major public health threat is feasible with the tools and approaches currently available. Effective vaccines are available for preventing viral hepatitis A, B and E infections. New oral, well-tolerated treatment regimens for chronic hepatitis C patients can achieve cure rates of over 90%. Effective treatment is also available for people with chronic hepatitis B virus infection; although for most people such treatment needs to be long-term, and recent advanced aim at a "functional cure" of hepatitis B. In this review article, we discuss the most recent advances of the diagnosis and treatment of viral hepatitis.

Indexed as

CirrhosisDirect antiviral agentsHepatic CHepatitis AHepatitis BHepatitis DHepatitis EHepatocellular carcinoma

Identifiers

PMID34267829
PMCPMC8256899
OpenAlexW3173442687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.