Evidence map›Paper›PMID 34267787›Full record

ReviewJornal vascular brasileiro2021

Vascular involvement in Behçet's disease: the immunopathological process.

Raquelle Machado de Vargas, Maria Luiza Nunes da Cruz, Maria Paula Hashimoto Giarllarielli, Beatriz Mota Sano, Geovana Idelfoncio da Silva, Karina Furlani Zoccal, Cristiane Tefé-Silva

Abstract readReview
In one paragraph

Review in Jornal vascular brasileiro, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Age-related immunosenescence in Behçet's disease.Rheumatology international · 2022
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raquelle Machado de VargasCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.
Maria Luiza Nunes da CruzCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.
Maria Paula Hashimoto GiarllarielliCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.
Beatriz Mota SanoCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.
Geovana Idelfoncio da SilvaCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.
Karina Furlani ZoccalCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.
Cristiane Tefé-SilvaCentro Universitário Barão de Mauá, Ribeirão Preto, SP, Brasil.ORCID 0000-0002-4657-032X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's disease is a rare form of systemic vasculitis that affects small to large vessels. It is characterized by mucocutaneous, pulmonary, cardiovascular, gastrointestinal, and neurological manifestations. Its clinical presentation is quite wide, ranging from milder cases to severe cases, with multisystemic involvement, characteristically with exacerbations and remissions. Its etiopathogenesis is still unclear, although there is evidence of genetic, environmental, and immunological factors, such as the association with the HLA-B51 allele. In conjunction, all of these point to an abnormal immunopathological process, with activation of cells of innate and adaptive immunity, such as NK cells, neutrophils, and T cells, which generate specific response patterns and cytokines capable of generating mediators that can damage and inflame blood vessels, resulting in venous and arterial occlusions and/or aneurysm formation.

Indexed as

Behçet syndromeHLA-B51 antigensystemic vasculitis

Identifiers

PMID34267787
PMCPMC8256877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.