Evidence map›Paper›PMID 34267729›Full record

ArticleFrontiers in endocrinology2021

Epigenetic Changes in Neonates Born to Mothers With Gestational Diabetes Mellitus May Be Associated With Neonatal Hypoglycaemia.

Yoshifumi Kasuga, Tomoko Kawai, Kei Miyakoshi, Yoshifumi Saisho, Masumi Tamagawa, Keita Hasegawa, Satoru Ikenoue, Daigo Ochiai, Mariko Hida, Mamoru Tanaka and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Transient fetal hyperglycemia reprograms adipogenesis, lipogenesis, and insulin signaling in zebrafish.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
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  8. National Center Biobank Network.Human genome variation · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yoshifumi KasugaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Tomoko KawaiDepartment of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Kei MiyakoshiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Yoshifumi SaishoDepartment of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Masumi TamagawaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Keita HasegawaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Satoru IkenoueDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Daigo OchiaiDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Mariko HidaDepartment of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
Mamoru TanakaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Kenichiro HataDepartment of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
Keio University · JPNational Center For Child Health and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of epigenetic changes associated with neonatal hypoglycaemia may reveal the pathophysiology and predict the onset of future diseases in offspring. We hypothesized that neonatal hypoglycaemia reflects the

Indexed as

DNA MethylationAdultAllelesBlood GlucoseDiabetes, GestationalFemaleGene FrequencyHumansHypoglycemiaInfant, NewbornInfant, Newborn, DiseasesMiddle AgedPregnancyBlood GlucoseDNA methylationepigeneticsgestational diabetes mellitusneonatal hypoglycaemiaumbilical cord blood

Identifiers

PMID34267729
PMCPMC8276691
OpenAlexW3173353052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.