Evidence map›Paper›PMID 34267609›Full record

ArticleEXCLI journal2021

Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway.

Da Hye Kwon, Gi-Young Kim, Hee-Jae Cha, Suhkmann Kim, Heui-Soo Kim, Hye-Jin Hwang, Yung Hyun Choi

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in EXCLI journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Da Hye KwonAnti-Aging Research Center, Dong-eui University, Busan, Republic of Korea.
Gi-Young KimDepartment of Marine Life Science, School of Marine Biomedical Sciences, Jeju National University, Jeju, Republic of Korea.
Hee-Jae ChaDepartment of Parasitology and Genetics, College of Medicine, Kosin University, Busan, Republic of Korea.
Suhkmann KimDepartment of Chemistry, College of Natural Sciences, Pusan National University, Busan, Republic of Korea.
Heui-Soo KimDepartment of Biological Sciences, College of Natural Sciences, Pusan National University, Busan, Republic of Korea.
Hye-Jin HwangDepartment of Food and Nutrition, College of Nursing, Healthcare Sciences & Human Ecology, Dong-eui University, Busan, Republic of Korea.
Yung Hyun ChoiAnti-Aging Research Center, Dong-eui University, Busan, Republic of Korea.ORCID https://orcid.org/0000-0002-1454-3124
Dong-Eui University · KRPusan National University · KRJeju National University · KRKosin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation caused by the excessive production of pro-inflammatory mediators and cytokines in abnormally activated macrophages promotes the initiation and progression of many diseases along with oxidative stress. Previous studies have suggested that nargenicin A1, an antibacterial macrolide isolated from

Indexed as

inflammationnargenicin A1NF-kappaBROS

Identifiers

PMID34267609
PMCPMC8278209
OpenAlexW3180000489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.