ArticleInternational journal of general medicine2021
Study on the Optic Nerve Fiber Layer Thickness and Changes in Blood Flow in Myopic Children.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Correlation between refractive errors and ocular biometric parameters in children and adolescents: a systematic review and meta-analysis.BMC ophthalmology · 2023Pooled it
- Assessment of choriocapillary flow deficits in myopic children by optical coherence tomography angiography.Scientific reports · 2025Article
- Papillary and peripapillary vascular densities and corresponding correlation with peripapillary retinal thicknesses using optical coherence tomography angiography in healthy children and adolescents.Scientific reports · 2024Article
- Protective effects of docosahexaenoic acid combined with bilberry extract on myopic Guinea pigs.Frontiers in medicine · 2024Article
- Compartmental analysis of retinal vascular parameters and thickness in myopic eyes using SS-OCTA.Frontiers in medicine · 2024Article
- Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography.Investigative ophthalmology & visual science · 2022Article
- Altered retinal nerve fiber layer thickness in children with allergic conjunctivitis: the Nanjing eye study.BMC ophthalmology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe present study aims to observe the optic nerve fiber layer thickness and blood flow density in the papillary area and investigate the effects of axial length (AL) and the refractive state of the optic papilla blood flow density in children with different refractive conditions.
methodsThe present study was a clinical control study. The right eyes of 204 minors aged 6-17 years were studied. The eyes were divided into four groups according to myopic refractive states. OCTA analyzed the data to compare the radial peripapillary capillary (RPC) density and the difference in the retinal nerve fiber layer (RNFL) thickness adjacent to the optic papilla between the four refraction groups.
resultsThe intra-optic disc blood flow density was significantly and negatively correlated with the AL and was negatively correlated with the AL in the inferior temporal quadrants. The RNFL in the superior, nasal, and inferior quadrants was negatively correlated with the AL. The RNFL in the temporal quadrant was positively correlated with the AL.
conclusionOur present study revealed that aAs myopia increased and the AL grew in children, the blood density of the entire image of the optic papilla, in the optic disc, and the retinal capillaries in the inferior parapapillary and temporal quadrant would change significantly. With increasing AL, a significant decrease in the intra-disc and para-disc RNFL was observed in the superior, nasal, and inferior quadrants, while a substantial increase in RNFL was observed in the temporal quadrant.
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