Evidence map›Paper›PMID 34267439›Full record

ArticleIndian journal of nephrology

Relation between Vitamin D Level and Cyclin-Dependent Kinase-1 Gene Expression in Egyptian Patients with Lupus Nephritis and their Impact on Disease Activity.

Eman M A Osman, Salma Y Abu El Nazar, Dalia A Maharem, Dhargam M Al-Jebouri, Iman S Naga

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Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Eman M A OsmanDepartment of Immunology and Allergy Medical Research Institute, Alexandria University, Alexandria, Egypt.
Salma Y Abu El NazarDepartment of Immunology and Allergy Medical Research Institute, Alexandria University, Alexandria, Egypt.
Dalia A MaharemInternal Medicine, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Dhargam M Al-JebouriNational Blood Transfusion Center, Iraq Ministry of Health, Baghdad, Iraq.
Iman S NagaMicrobiology, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Alexandria University · EGMinistry of Health · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLupus nephritis (LN) is a common complication of systemic lupus erythematosus. Vitamin D and cycline-dependent kinase-1 (CDK1) have been implicated in its pathogenesis. The aim of this study was to determine the relation between vitamin D level and CDK-1 in lupus nephritis patients and their impact on disease activity. PATIENTS AND

methodsThe current study was conducted on 50 LN patients and 20 control subjects from Egyptian population using ELISA to assess vitamin D level in serum and TaqMan assay for CDK1 gene expression.

resultsSerum vitamin D level was significantly lower in LN patients and

conclusionsVitamin D deficiency acts as a risk factor for developing LN.

Indexed as

CDK-1lupus nephritissystemic lupus erythematosusvitamin D

Identifiers

PMID34267439
PMCPMC8240929
OpenAlexW3147393564

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.