ArticleNature genetics2021
Haplotype-resolved genome assembly provides insights into evolutionary history of the tea plant Camellia sinensis.
Article in Nature genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 183 papers.
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183 citing papers in PubMed.
- The heterozygous pineapple genome demonstrates the importance of haplotype-resolved plant genomes.Horticulture research · 2026Article
- The highly heterozygous European amphioxus (Branchiostoma lanceolatum) at the edge of panmixia.PLoS genetics · 2026Article
- Haplotype-resolved regulation of secondary metabolism in cannabis.Horticulture research · 2026Article
- Article
- Comparative Genomics of the TeaInternational journal of molecular sciences · 2026Article
- Assessment of the Genetic Diversity and Population Structure of a Wild Tea Germplasm Collection in Thailand Using SSR Markers.Plants (Basel, Switzerland) · 2026Article
- Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY-CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis.Plant biotechnology journal · 2026Article
- Comparative chloroplast genome analysis reveals genetic differentiation and maternal introgression in tea plants (Camellia sinensis) from Shaoyang, China.BMC plant biology · 2026Article
- Integrated metabolomic and transcriptomic analysis of Camellia sinensis var. pubilimba 'Rucheng Baimaocha' reveals distinct flavonoid and strictinin biosynthesis.BMC plant biology · 2026Article
- Chromosome-level genome assembly of oil-tea tree Camellia brevistyla.Scientific data · 2026Article
- Post-polyploid chromosomal diploidization in plants is affected by clade divergence and constrained by shared genomic features.Nature communications · 2026Article
- Haplotype-resolved genome of 'Pinot Noir' reveals DNA polymorphisms and allele-specific expression shaping terroir adaptation.Molecular horticulture · 2026Article
- Identification of a unique tea germplasm exhibiting hyperaccumulation of trans-catechins and its molecular regulatory mechanism.Food chemistry. Molecular sciences · 2026Article
- A haplotype-resolved nutmeg genome reveals XY sex chromosome evolution and enables molecular sexing.Communications biology · 2026Article
- ddRAD sequencing of 1076Plant diversity · 2026Article
- Genetic diversity and population structure of wild and cultivated Camellia tetracocca Chang assessed by ILP markers: insights for conservation of an endangered tea species.BMC plant biology · 2026Article
- Haplotype-resolved genome assembly provides insights into the unique floral scent of Rosa rugosa originated in China.Molecular horticulture · 2026Article
- Haplotype-resolved genome assembly provides insights into the evolutionary origin of waterlogging-tolerantHorticulture research · 2026Article
- From structural pangenomes to functional panomics in plants.Molecular biology and evolution · 2026Review
- Spatial transcriptome analysis of the tea tender shoot sheds light on transcriptional regulation of characteristic metabolites.Horticulture research · 2026Article
123 more citing papers are in PubMed but not listed here.
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33 authors.
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Abstract
Tea is an important global beverage crop and is largely clonally propagated. Despite previous studies on the species, its genetic and evolutionary history deserves further research. Here, we present a haplotype-resolved assembly of an Oolong tea cultivar, Tieguanyin. Analysis of allele-specific expression suggests a potential mechanism in response to mutation load during long-term clonal propagation. Population genomic analysis using 190 Camellia accessions uncovered independent evolutionary histories and parallel domestication in two widely cultivated varieties, var. sinensis and var. assamica. It also revealed extensive intra- and interspecific introgressions contributing to genetic diversity in modern cultivars. Strong signatures of selection were associated with biosynthetic and metabolic pathways that contribute to flavor characteristics as well as genes likely involved in the Green Revolution in the tea industry. Our results offer genetic and molecular insights into the evolutionary history of Camellia sinensis and provide genomic resources to further facilitate gene editing to enhance desirable traits in tea crops.
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