ArticleMolecular psychiatry2021
Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using
Open access · hybridAbstract read
In one paragraph
Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- In vivo quantitative imaging of hippocampal inflammation in autoimmune neuroinflammatory conditions: a systematic review.Clinical and experimental immunology · 2022Pooled it
- Imaging the interaction of astrocytes and neurons.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Recent advances in Alzheimer's disease: From molecular mechanisms to therapeutic strategies.Cell · 2026Review
- Co-pathologies and biological processes beyond amyloid-beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies.Journal of internal medicine · 2026Review
- Curing the brain: in search for new astrocyte-specific therapies.Experimental & molecular medicine · 2026Review
- Increased levels of GFAP and purinergic P2X7 receptor in Alzheimer's disease brain are associated with Aβ, tau pathologies and synaptic loss.Alzheimer's research & therapy · 2025Article
- Advance and Prospect of Positron Emission Tomography in Alzheimer's disease research.Molecular psychiatry · 2025Review
- Choroid plexus free-water correlates with glymphatic function in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Cerebrospinal fluid β2-microglobulin promotes the tau pathology through microglia-astrocyte communication in Alzheimer's disease.Alzheimer's research & therapy · 2025Article
- PET imaging of neuroinflammation: any credible alternatives to TSPO yet?Molecular psychiatry · 2025Review
- Neuroinflammatory Biomarkers in Alzheimer's Disease: From Pathophysiology to Clinical Implications.International journal of molecular sciences · 2024Review
- The development status of PET radiotracers for evaluating neuroinflammation.Nuclear medicine and molecular imaging · 2024Review
- Astroglial activation: Current concepts and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Associations of amyloid-β oligomers and plaques with neuropathology in theBrain communications · 2024Article
- PET Imaging to Measure Neuroinflammation In Vivo.Methods in molecular biology (Clifton, N.J.) · 2024Article
- The use of neuroimaging techniques in the early and differential diagnosis of dementia.Molecular psychiatry · 2023Review
- Imidazoline-I2 PET Tracers in Neuroimaging.International journal of molecular sciences · 2023Review
- Astrocyte Signature in Alzheimer's Disease Continuum through a Multi-PET Tracer Imaging Perspective.Cells · 2023Review
- Advances in Molecular Psychiatry - March 2023: mitochondrial function, stress, neuroinflammation - bipolar disorder, psychosis, and Alzheimer's disease.Molecular psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 7 institutions in 2 countries.
Valeria CalsolaroDepartment of Brain Sciences, Imperial College London, London, UK.
Paul M MatthewsDepartment of Brain Sciences, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-1619-8328
Cornelius K DonatDepartment of Brain Sciences, Imperial College London, London, UK.
Nicholas R LivingstonDepartment of Brain Sciences, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-6582-2545
Grazia D FemminellaDepartment of Brain Sciences, Imperial College London, London, UK.
Sandra Silva GuedesDepartment of Brain Sciences, Imperial College London, London, UK.
Jim MyersDepartment of Brain Sciences, Imperial College London, London, UK.
Zhen FanDepartment of Brain Sciences, Imperial College London, London, UK.
Robin J TyackeDepartment of Brain Sciences, Imperial College London, London, UK.
Ashwin V VenkataramanDepartment of Brain Sciences, Imperial College London, London, UK.
Robert PerneczkyDepartment of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Roger GunnDepartment of Brain Sciences, Imperial College London, London, UK.
Eugenii A RabinerInvicro, London, UK.ORCID http://orcid.org/0000-0003-3612-6687
Steve GentlemanDepartment of Brain Sciences, Imperial College London, London, UK.
Christine A ParkerDepartment of Brain Sciences, Imperial College London, London, UK.
Philip S MurphyGlaxoSmithKline, Stevenage, UK.
Paul B WrenGlaxoSmithKline, Stevenage, UK.
Rainer HinzWolfson Molecular Imaging Centre, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-7808-9207
Magdalena SastreDepartment of Brain Sciences, Imperial College London, London, UK.
David J NuttDepartment of Brain Sciences, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-1286-1401
Paul EdisonDepartment of Brain Sciences, Imperial College London, London, UK. paul.edison@imperial.ac.uk.ORCID http://orcid.org/0000-0002-6551-2002
Imperial College London · GBGlaxoSmithKline (United Kingdom) · GBGerman Center for Neurodegenerative Diseases · DEInvicro (United Kingdom) · GBKing's College London · GBUK Dementia Research Institute · GBUniversity of Manchester · GB
Funding
Department of HealthMedical Research Council G0100811Medical Research Council G0300665Medical Research Council G0601966Medical Research Council G0900897Medical Research Council G9409531Medical Research Council G9409634Medical Research Council G9901399Medical Research Council MC_PC_17114Medical Research Council MR/K501013/1Medical Research Council MR/M024903/1Medical Research Council MR/N026934/1Medical Research Council MR/T033371/1
Abstract
PubMed holds no abstract for this paper.
Indexed as
Alzheimer DiseaseCognitive DysfunctionAmyloid beta-PeptidesAniline CompoundsAstrocytesBrainHumansImidazolesIndolesPositron-Emission Tomography2-(4,5-dihydro-1H-imidazol-2-yl)-1-methyl-1H-indoleAmyloid beta-PeptidesAniline CompoundsImidazolesIndoles
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.