Evidence map›Paper›PMID 34267273›Full record

ArticleScientific reports2021

Medial prefrontal cortex (A32 and A25) projections in the common marmoset: a subcortical anterograde study.

Jorge Alexander Ríos-Flórez, Ruthnaldo R M Lima, Paulo Leonardo A G Morais, Helder Henrique Alves de Medeiros, Jeferson Souza Cavalcante, Expedito S Nascimento Junior

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Ultra-high Field fMRI Reveals Effect of Ketamine on Vocal Processing in Common Marmosets.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Review
  4. Retinorecipient areas in the common marmoset (Frontiers in neural circuits · 2023
    Review
  5. Brain and cardiovascular-related changes are associated with aging, hypertension, and atrial fibrillation.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jorge Alexander Ríos-FlórezNeuroanatomy Laboratory, Department of Morphology, Federal University of Rio Grande Do Norte, Natal, Brazil. alexander.rios@ufrn.edu.br.
Ruthnaldo R M LimaNeuroanatomy Laboratory, Department of Morphology, Federal University of Rio Grande Do Norte, Natal, Brazil.
Paulo Leonardo A G MoraisLaboratory of Experimental Neurology, the University of the State of Rio Grande Do Norte, Mossoro, Brazil.
Helder Henrique Alves de MedeirosNeuroanatomy Laboratory, Department of Morphology, Federal University of Rio Grande Do Norte, Natal, Brazil.
Jeferson Souza CavalcanteLaboratory for Neurochemical Studies, Federal University of Rio Grande Do Norte, Natal, Brazil.
Expedito S Nascimento JuniorNeuroanatomy Laboratory, Department of Morphology, Federal University of Rio Grande Do Norte, Natal, Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade do Estado do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was aimed at establishing the subcorticals substrates of the cognitive and visceromotor circuits of the A32 and A25 cortices of the medial prefrontal cortex and their projections and interactions with subcortical complexes in the common marmoset monkey (Callithrix jacchus). The study was primarily restricted to the nuclei of the diencephalon and amygdala. The common marmoset is a neotropical primate of the new world, and the absence of telencephalic gyrus favors the mapping of neuronal fibers. The biotinylated dextran amine was employed as an anterograde tracer. There was an evident pattern of rostrocaudal distribution of fibers within the subcortical nuclei, with medial orientation. Considering this distribution, fibers originating from the A25 cortex were found to be more clustered in the diencephalon and amygdala than those originating in the A32 cortex. Most areas of the amygdala received fibers from both cortices. In the diencephalon, all regions received projections from the A32, while the A25 fibers were restricted to the thalamus, hypothalamus, and epithalamus at different densities. Precise deposits of neuronal tracers provided here may significantly contribute to expand our understanding of specific connectivity among the medial prefrontal cortex with limbic regions and diencephalic areas, key elements to the viscerocognitive process.

Indexed as

CallithrixAmygdalaAnimalsBiotinBrain MappingDextransFemaleHypothalamusMaleNeural PathwaysPrefrontal CortexStereotaxic TechniquesThalamusBiotinbiotinylated dextran amineDextrans

Identifiers

PMID34267273
PMCPMC8282874
OpenAlexW3180289106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.