Evidence map›Paper›PMID 34266852›Full record

ArticleBMJ open respiratory research2021

Web-based survey to evaluate the prevalence of chronic and subacute cough and patient characteristics in Japan.

Keisuke Tobe, Takekazu Kubo, Kotoba Okuyama, Masashi Kikuchi, Yirong Chen, Jonathan Schelfhout, Machiko Abe, Shigeru Tokita

Abstract read
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Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Keisuke TobeMSD KK, Tokyo, Japan.
Takekazu KuboMSD KK, Tokyo, Japan takekazu.kubo@merck.com.
Kotoba OkuyamaMSD KK, Tokyo, Japan.
Masashi KikuchiMSD KK, Tokyo, Japan.
Yirong ChenKantar Health, Singapore.
Jonathan SchelfhoutMerck & Co Inc, Kenilworth, New Jersey, USA.
Machiko AbeMSD KK, Tokyo, Japan.
Shigeru TokitaMSD KK, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCough lasting 3-8 weeks and more than 8 weeks are defined as subacute/prolonged cough and chronic cough, respectively. Japanese chronic cough population has not been well studied. This study aimed to describe the prevalence and characteristics of chronic cough and subacute cough patients in Japan. This study also sought to compare between chronic cough patients who were not greatly satisfied with treatment effectiveness for resolving cough and other chronic cough patients.

methodsData from a cross-sectional online 2019 Japan National Health and Wellness Survey and a supplemental chronic cough survey were used to understand respondents' chronic cough status and their cough-specific characteristics and experience. The prevalence, patient characteristics and cough-specific characteristics were summarised descriptively. Patients who were not greatly satisfied with treatment effectiveness and other chronic cough patients were compared for their characteristics and cough severity.

resultsThe point prevalence of chronic cough was 2.89% and 12-month period prevalence was 4.29%. Among all chronic cough patients analysed, the average age was 56 years old, 61.1% were males and 29.4% were current smokers. Patients were most frequently told by a physician that cough was related to allergic rhinitis, asthma and cough variant asthma. Only 44.2% of chronic cough patients had spoken with a physician about their cough, and half of chronic cough patients did not use any medications. Patients who were not greatly satisfied with treatment effectiveness had significantly greater cough severity during past 2 weeks compared with other chronic cough patients (Visual Analogue Scale 45.34 vs 39.63).

conclusionsThis study described the prevalence and patient characteristics information of chronic cough patients in Japan. Furthermore, the study highlighted an unmet need for better diagnosis and treatments for chronic cough patients, especially among patients who were not greatly satisfied with treatment effectiveness and reported significantly worse cough severity.

Indexed as

CoughInternetCross-Sectional StudiesHumansJapanMaleMiddle AgedPrevalenceSurveys and Questionnairesclinical epidemiologycough/mechanisms/pharmacology

Identifiers

PMID34266852
PMCPMC8286770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.