Evidence map›Paper›PMID 34266811›Full record

ArticleHematology, transfusion and cell therapy

Evaluation of RET-He values as an early indicator of iron deficiency anemia in pregnant women.

Suzane Dal Bó, Ana Luiza Rodrigues Fragoso, Mariela Granero Farias, Dariana Pimentel Gomes Hubner, Simone Martins de Castro

Abstract read
In one paragraph

Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suzane Dal BóHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. Electronic address: simone.castro@ufrgs.br.
Ana Luiza Rodrigues FragosoFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul (FacFar UFRGS), Porto Alegre, RS, Brazil.
Mariela Granero FariasHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Dariana Pimentel Gomes HubnerFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul (FacFar UFRGS), Porto Alegre, RS, Brazil.
Simone Martins de CastroFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul (FacFar UFRGS), Porto Alegre, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDuring pregnancy, women are at an increased risk of developing iron-deficiency anemia.

objectiveThe objective of this study was to assess the diagnostic performance of the reticulocyte hemoglobin equivalent (RET-He) in the early detection of iron-deficiency anemia in a group of pregnant women and to establish a reference range for this parameter in a group of control individuals.

methodA total of 60 patients and 130 control subjects were included in the study. Blood samples collected from the subjects were submitted to a complete blood count and a serum ferritin test and the data were analyzed by comparing the groups and ROC curves.

resultsThe reference range found for the RET-He was between 29.75pg and 38.24pg, with a median of 35pg. The receiver operating characteristic (ROC) curve analysis for the ferritin parameter showed an area under the curve of 0.732 for the RET-He, 0.586 for hemoglobin, 0.551 for the mean corpuscular hemoglobin concentration and 0.482 for the mean corpuscular volume.

conclusionEarly diagnosis of iron deficiency anemia in pregnancy is essential to prevent damage to both maternal and fetal health. The RET-He presents an excellent potential as an auxiliary tool for the diagnosis of iron deficiency in pregnant women.

Indexed as

AnemiaHematology analyzersIron deficiencyPregnancy diagnosisRET-HeReticulocytes

Identifiers

PMID34266811
PMCPMC9938494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.