Evidence map›Paper›PMID 34266675›Full record

ReviewSeminars in perinatology2021

Maternal microbial factors that affect the fetus and subsequent offspring.

Julie Mirpuri, Josef Neu

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in perinatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Julie MirpuriDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: Julie.mirpuri@utsouthwestern.edu.
Josef NeuDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Florida, Gainesville, FL, USA.
Southwestern Medical CenterUniversity of Florida · US

Funding

Mechanisms of maternal high fat diet induced susceptibility to gut inflammation in offspringR01DK121975 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MIRPURI-HATHIRAMANI, JULIE · 2020 to 2024
$1.8M
NIDDK NIH HHS R01 DK121975
6 · The paper itself

Abstract

The maternal microbiome has emerged as an important area of investigation. While birth is a critical timepoint for initial colonization of the newborn, the fetus resides in the womb surrounded by multiple unique colonized niches. The maternal microbiome has recently been shown to be associated with several morbidities in offspring. Understanding the multiple bacterial niches within the pregnant woman and how they interact with the fetus in-utero can lead to novel therapies to improve the health of offspring. In this review, we provide an overview of the available literature on normal bacterial colonization within the individual niches of the pregnant woman and the known associations with outcomes in offspring, including a discussion of the controversy of in-utero colonization.

Indexed as

FetusMicrobiotaBacteriaFemaleHumansPregnancyUterusfetusMaternalmicrobiomeoffspringprobiotics

Identifiers

PMID34266675
PMCPMC8440431
OpenAlexW3174114211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.